Introduction Sulfur-containing functional groups are privileged motifs that occur in various
pharmacologically effective substances and several natural products. Various functionalities …

Prostate cancer is a hormone-dependent malignancy, whose onset and progression are
closely related to the activity of the androgen receptor (AR) signaling pathway. Due to this …

The development of novel drug modalities is necessary to overcome the current critical
issues in the treatment of cancer, namely toxicity, insufficient efficacy, and the development …

Due to late onset hypogonadism (LOH), there is an increased usage of testosterone
replacement therapy (TRT) in the aging male population. Since prostate is a target organ for …

Drug resistance represents a major obstacle to therapeutic innovations and is a prevalent
feature in prostate cancer (PCa). Androgen receptors (ARs) are the hallmark therapeutic …

Anabolic androgenic steroids (AAS) are substances with androgenic and anabolic
characteristics. Among the many side effects of hormone therapy with AAS, the following …

Resistance to androgen receptor (AR)–targeted therapies for prostate cancer (PCa) is
characteristic of an aggressive subtype called castration-resistant prostate cancer (CRPC) …

Androgen receptor (AR) is a key contributing element in the prostate cancer (PCa)
instigation, progression and it is among the vastly discovered target for prostate cancer …

In the current study, we utilized molecular modeling and simulation approaches to define
putative potential molecular targets for Burdock Inulin, including inflammatory proteins such …

Androgen receptor (AR) signaling is essential in prostate cancer treatment. For many years,
androgen deprivation therapy (ADT) has been primarily applied to manage advanced …