Small interfering RNA: Discovery, pharmacology and clinical development—An introductory review
P Ranasinghe, ML Addison, JW Dear… - British Journal of …, 2023 - Wiley Online Library
Post‐transcriptional gene silencing targets and degrades mRNA transcripts, silencing the
expression of specific genes. RNA interference technology, using synthetic structurally well …
expression of specific genes. RNA interference technology, using synthetic structurally well …
NRF2 signalling in cytoprotection and metabolism
S Murakami, Y Kusano, K Okazaki… - British Journal of …, 2023 - Wiley Online Library
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms
against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing …
against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing …
The IUPHAR/BPS guide to PHARMACOLOGY in 2024
SD Harding, JF Armstrong, E Faccenda… - Nucleic acids …, 2024 - academic.oup.com
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb; https://www.
guidetopharmacology. org) is an open-access, expert-curated, online database that …
guidetopharmacology. org) is an open-access, expert-curated, online database that …
The IUPHAR/BPS guide to PHARMACOLOGY in 2022: curating pharmacology for COVID-19, malaria and antibacterials
SD Harding, JF Armstrong, E Faccenda… - Nucleic Acids …, 2022 - academic.oup.com
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb; www.
guidetopharmacology. org) is an open-access, expert-curated database of molecular …
guidetopharmacology. org) is an open-access, expert-curated database of molecular …
Leonurine alleviates ferroptosis in cisplatin‐induced acute kidney injury by activating the Nrf2 signalling pathway
J Hu, W Gu, N Ma, X Fan, X Ci - British journal of pharmacology, 2022 - Wiley Online Library
Background and purpose Evidence indicates that ferroptosis plays a key role in acute kidney
injury induced by cisplatin. The Nrf2/NRF2 pathway regulates oxidative stress, lipid …
injury induced by cisplatin. The Nrf2/NRF2 pathway regulates oxidative stress, lipid …
Short‐chain fatty acids regulate B cells differentiation via the FFA2 receptor to alleviate rheumatoid arthritis
Y Yao, X Cai, Y Zheng, M Zhang, W Fei… - British Journal of …, 2022 - Wiley Online Library
Background and Purpose Short‐chain fatty acids (SCFAs) are metabolites from gut microbes
involved in the host's inflammatory response and immunity. The aim of this study was to …
involved in the host's inflammatory response and immunity. The aim of this study was to …
Transcriptome‐level discovery of survival‐associated biomarkers and therapy targets in non‐small‐cell lung cancer
B Győrffy - British Journal of Pharmacology, 2024 - Wiley Online Library
Abstract Background and Purpose Survival rate of patients with lung cancer has increased
by over 60% in the recent two decades. With longer survival, the identification of genes …
by over 60% in the recent two decades. With longer survival, the identification of genes …
Safety and efficacy of fluvoxamine in COVID‐19 ICU patients: an open label, prospective cohort trial with matched controls
M Calusic, R Marcec, L Luksa, I Jurkovic… - British journal of …, 2022 - Wiley Online Library
Aims Fluvoxamine, a selective serotonin reuptake inhibitor (SSRI) and sigma‐1 receptor
agonist, has so far shown promise in the prevention of COVID‐19 progression as an early …
agonist, has so far shown promise in the prevention of COVID‐19 progression as an early …
[BOOK][B] Principles of computational modelling in neuroscience
D Sterratt, B Graham, A Gillies, G Einevoll, D Willshaw - 2023 - books.google.com
Taking a step-by-step approach to modelling neurons and neural circuitry, this textbook
teaches students how to use computational techniques to understand the nervous system at …
teaches students how to use computational techniques to understand the nervous system at …
Honokiol ameliorates cisplatin‐induced acute kidney injury via inhibition of mitochondrial fission
R Mao, S He, J Lan, W Zhu - British Journal of Pharmacology, 2022 - Wiley Online Library
Background and Purpose Mitochondrial damage and oxidative stress are crucial
contributors to the tubular cell injury and death in acute kidney injury. Novel therapeutic …
contributors to the tubular cell injury and death in acute kidney injury. Novel therapeutic …