In vitro mineralization of collagen

BM Oosterlaken, MP Vena, G de With - Advanced Materials, 2021 - Wiley Online Library
Collagen mineralization is a biological process in many skeletal elements in the animal
kingdom. Examples of these collagen‐based skeletons are the siliceous spicules of glass …

Biomimetic model systems for investigating the amorphous precursor pathway and its role in biomineralization

LB Gower - Chemical reviews, 2008 - ACS Publications
Biologically formed hard tissues, referred to as biominerals, have intrigued the materials
engineering community for years because of the high degree of crystallographic control that …

The role of collagen in bone apatite formation in the presence of hydroxyapatite nucleation inhibitors

F Nudelman, K Pieterse, A George, PHH Bomans… - Nature materials, 2010 - nature.com
Bone is a composite material in which collagen fibrils form a scaffold for a highly organized
arrangement of uniaxially oriented apatite crystals,. In the periodic 67 nm cross-striated …

Limitations in bonding to dentin and experimental strategies to prevent bond degradation

Y Liu, L Tjäderhane, L Breschi… - Journal of dental …, 2011 - journals.sagepub.com
The limited durability of resin-dentin bonds severely compromises the lifetime of tooth-
colored restorations. Bond degradation occurs via hydrolysis of suboptimally polymerized …

Hierarchical structures of bone and bioinspired bone tissue engineering

Y Liu, D Luo, T Wang - Small, 2016 - Wiley Online Library
Bone, as a mineralized composite of inorganic (mostly carbonated hydroxyapatite) and
organic (mainly type I collagen) phases, possesses a unique combination of remarkable …

Advances in biomineralization-inspired materials for hard tissue repair

S Tang, Z Dong, X Ke, J Luo, J Li - International journal of oral science, 2021 - nature.com
Biomineralization is the process by which organisms form mineralized tissues with
hierarchical structures and excellent properties, including the bones and teeth in …

The predominant role of collagen in the nucleation, growth, structure and orientation of bone apatite

Y Wang, T Azaïs, M Robin, A Vallée, C Catania… - Nature materials, 2012 - nature.com
The involvement of collagen in bone biomineralization is commonly admitted, yet its role
remains unclear. Here we show that type I collagen in vitro can initiate and orientate the …

Biomineralization of collagen-based materials for hard tissue repair

L Yu, M Wei - International journal of molecular sciences, 2021 - mdpi.com
Hydroxyapatite (HA) reinforced collagen fibrils serve as the basic building blocks of natural
bone and dentin. Mineralization of collagen fibrils play an essential role in ensuring the …

Collagen intrafibrillar mineralization as a result of the balance between osmotic equilibrium and electroneutrality

LN Niu, SE Jee, K Jiao, L Tonggu, M Li, L Wang… - Nature materials, 2017 - nature.com
Mineralization of fibrillar collagen with biomimetic process-directing agents has enabled
scientists to gain insight into the potential mechanisms involved in intrafibrillar …

Map** amorphous calcium phosphate transformation into crystalline mineral from the cell to the bone in zebrafish fin rays

J Mahamid, B Aichmayer, E Shimoni… - Proceedings of the …, 2010 - National Acad Sciences
The continuously forming fin bony rays of zebrafish represent a simple bone model system
in which mineralization is temporally and spatially resolved. The mineralized collagen fibrils …