The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …

Platinum-based anticancer drugs have been widely applied in clinical settings for more than
40 years. The remarkable breakthroughs that have come from the use of these complexes in …

Direct condensation of 2-acetylferrocene with tris (2-aminoethyl) amine resulted in a novel
tripodal imine ligand (L). Treatment of the metals' chlorides (Fe 3+, Cr 3+, Co 2+, Ni 2+, Cu …

Fragment-based drug discovery (FBDD) is a powerful strategy for the identification of new
bioactive molecules. FBDD relies on fragment libraries, generally of modest size, but of high …

The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …

In pursuit of better treatment options for malignant tumors, metal-based complexes continue
to show promise as attractive chemotherapeutics due to tunability, novel mechanisms, and …

Noble bimetallic and trimetallic nanoparticles (NBT-NPs) have superior biomedical
applications as compared to their monometallic counterparts. The performance of these …

In recent years, both metal-based complexes and selenium-containing compounds have
been widely explored for their therapeutic properties due to their roles in biological …

Platinum-based anticancer drugs currently available in the market are associated with
severe side effects. Therefore, extensive research has been performed to design and …

The coumarin nucleus is a recurring motif in both natural and synthetic compounds that
exhibit a broad spectrum of biological properties including anticoagulant, anti-inflammatory …