Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA

P Wu, Y Mo, M Peng, T Tang, Y Zhong, X Deng… - Molecular cancer, 2020 - Springer
Non-coding RNAs do not encode proteins and regulate various oncological processes. They
are also important potential cancer diagnostic and prognostic biomarkers. Bioinformatics …

Circular RNAs act as miRNA sponges

AC Panda - Circular RNAs: biogenesis and functions, 2018 - Springer
Majority of RNAs expressed in animal cells lack protein-coding ability. Unlike other cellular
RNAs, circular (circ) RNAs include a large family of noncoding (nc) RNAs that lack the 5′ or …

Circular RNAs: promising biomarkers for human diseases

Z Zhang, T Yang, J **ao - EBioMedicine, 2018 - thelancet.com
Circular RNA (circRNA) is a group of endogenous noncoding RNA characterized by a
covalently closed cyclic structure lacking poly-adenylated tails. Recent studies have …

Circular RNAs function as ceRNAs to regulate and control human cancer progression

Y Zhong, Y Du, X Yang, Y Mo, C Fan, F **ong, D Ren… - Molecular cancer, 2018 - Springer
Circular RNAs (circRNAs) are connected at the 3′ and 5′ ends by exon or intron
cyclization, forming a complete ring structure. circRNA is more stable and conservative than …

Circular RNAs and complex diseases: from experimental results to computational models

CC Wang, CD Han, Q Zhao, X Chen - Briefings in bioinformatics, 2021 - academic.oup.com
Circular RNAs (circRNAs) are a class of single-stranded, covalently closed RNA molecules
with a variety of biological functions. Studies have shown that circRNAs are involved in a …

[HTML][HTML] A novel axis of circKIF4A-miR-637-STAT3 promotes brain metastasis in triple-negative breast cancer

S Wu, J Lu, H Zhu, F Wu, Y Mo, L **e, C Song, L Liu… - Cancer Letters, 2024 - Elsevier
Among patients with triple-negative breast cancer (TNBC), distant metastasis is the leading
cause of death. Our previous studies have shown that TNBC progression is greatly …

CircRNAs in cancer metabolism: a review

T Yu, Y Wang, Y Fan, N Fang, T Wang, T Xu… - Journal of hematology & …, 2019 - Springer
Altered energy metabolism is a hallmark of tumors aiming at supplying necessary nutrients
for tumorigenesis and development. These redirected metabolic pathways associated with …

circRNA_0025202 regulates tamoxifen sensitivity and tumor progression via regulating the miR-182-5p/FOXO3a axis in breast cancer

Y Sang, B Chen, X Song, Y Li, Y Liang, D Han… - Molecular Therapy, 2019 - cell.com
Tamoxifen is the most commonly used endocrine therapy for patients with hormone receptor
(HR)-positive breast cancer. Despite its initial therapeutic efficacy, many patients eventually …

CircXRN2 suppresses tumor progression driven by histone lactylation through activating the Hippo pathway in human bladder cancer

B **e, J Lin, X Chen, X Zhou, Y Zhang, M Fan, J **ang… - Molecular Cancer, 2023 - Springer
Abstract Background Bladder cancer (BCa) is the fourth most common malignant tumor with
a poor prognosis worldwide. Further exploration and research are needed to unmask the …

Targets of immune escape mechanisms in cancer: basis for development and evolution of cancer immune checkpoint inhibitors

S Dutta, A Ganguly, K Chatterjee, S Spada… - Biology, 2023 - mdpi.com
Simple Summary The tumor immune escape mechanisms are key factors in cancer
progression and metastasis. They are an undeniable hurdle for successful cancer treatment …