Big data from electronic health records for early and late translational cardiovascular research: challenges and potential

H Hemingway, FW Asselbergs, J Danesh… - European heart …, 2018 - academic.oup.com
Aims Cohorts of millions of people's health records, whole genome sequencing, imaging,
sensor, societal and publicly available data present a rapidly expanding digital trace of …

The reporting of studies conducted using observational routinely collected health data statement for pharmacoepidemiology (RECORD-PE)

SM Langan, SAJ Schmidt, K Wing, V Ehrenstein… - bmj, 2018 - bmj.com
In pharmacoepidemiology, routinely collected data from electronic health records (including
primary care databases, registries, and administrative healthcare claims) are a resource for …

Integrated precision medicine: the role of electronic health records in delivering personalized treatment

A Sitapati, H Kim, B Berkovich… - … Systems Biology and …, 2017 - Wiley Online Library
Precision Medicine involves the delivery of a targeted, personalized treatment for a given
patient. By harnessing the power of electronic health records (EHRs), we are increasingly …

Validation of a common data model for active safety surveillance research

JM Overhage, PB Ryan, CG Reich… - Journal of the …, 2012 - academic.oup.com
Objective Systematic analysis of observational medical databases for active safety
surveillance is hindered by the variation in data models and coding systems. Data analysts …

Feasibility and utility of applications of the common data model to multiple, disparate observational health databases

EA Voss, R Makadia, A Matcho, Q Ma… - Journal of the …, 2015 - academic.oup.com
Objectives To evaluate the utility of applying the Observational Medical Outcomes
Partnership (OMOP) Common Data Model (CDM) across multiple observational databases …

Deep learning for pharmacovigilance: recurrent neural network architectures for labeling adverse drug reactions in Twitter posts

A Cocos, AG Fiks, AJ Masino - Journal of the American Medical …, 2017 - academic.oup.com
Objective Social media is an important pharmacovigilance data source for adverse drug
reaction (ADR) identification. Human review of social media data is infeasible due to data …

Synergies between centralized and federated approaches to data quality: a report from the national COVID cohort collaborative

ER Pfaff, AT Girvin, DL Gabriel, K Kostka… - Journal of the …, 2022 - academic.oup.com
Objective In response to COVID-19, the informatics community united to aggregate as much
clinical data as possible to characterize this new disease and reduce its impact through …

Data extraction for epidemiological research (DExtER): a novel tool for automated clinical epidemiology studies

KM Gokhale, JS Chandan, K Toulis, G Gkoutos… - European journal of …, 2021 - Springer
The use of primary care electronic health records for research is abundant. The benefits
gained from utilising such records lies in their size, longitudinal data collection and data …

[HTML][HTML] Data harmonization and federated learning for multi-cohort dementia research using the OMOP common data model: A Netherlands consortium of dementia …

P Mateus, J Moonen, M Beran, E Jaarsma… - Journal of biomedical …, 2024 - Elsevier
Background Establishing collaborations between cohort studies has been fundamental for
progress in health research. However, such collaborations are hampered by heterogeneous …

Desiderata for computable representations of electronic health records-driven phenotype algorithms

H Mo, WK Thompson, LV Rasmussen… - Journal of the …, 2015 - academic.oup.com
Abstract Background Electronic health records (EHRs) are increasingly used for clinical and
translational research through the creation of phenotype algorithms. Currently, phenotype …