Mechanochemistry approach is addressed herein for the green formation of a novel 1: 1
drug–drug cocrystal (DDC) involving the antifungal prodrug Flucytosine (5FC) and the non …

Caloric restriction mimetics (CRMs) are promising molecules to prevent age-related
diseases as they activate pathways driven by a true caloric restriction. Hydroxycitric acid …

Abstract Aspirin (Acetylsalicylic acid, ASA), one of the widely used non-steroid anti-
inflammatory drugs can easily end up in sewage effluents and thus it becomes necessary to …

Aspirin is a commonly used anti‐inflammatory, analgesic and antithrombotic drug. It has
attracted attention due to its potential antifungal therapeutic effect; however, the molecular …

Here, we investigated the biological effects of arachidonic acid (AA) in human cumulus
granulosa cells (CGCs) after exposure to ASA. Cells were isolated from the follicular fluid …

Pharmaceuticals have drawn attention due to the potential of causing negative impacts on
the population and ecosystems at ecological relevant concentrations. Among these …

Cancer cell proliferation and their adaptation to tough environments depend critically on
metabolic pathways. The pathological, phenotypic, and structural level understanding of …

Colorectal cancer (CRC) is the second highest cause of cancer-related mortality in the UK
and incidence is increasing, particularly in younger patients. 5-year survival rates in CRC …

There is an inter-individual variation in drug response to anti-cancer agents because it is a
complex trait controlled by multiple genes and environmental factors. This thesis explores …

Aspirin is a widely used anti-inflammatory and antithrombotic drug that exhibits
chemopreventive anti-tumor properties. Aspirin is considered to be partially mediated by the …