The ubiquitin‐proteasome system, which is one of the systems for cell protein homeostasis
and degradation, happens through the ordered and coordinated action of three types of …

Background Macrophages at infection sites are considered as the promising therapeutic
targets to prevent sepsis development. The Nrf2/Keap1 system acts as a critical modulator of …

Emerging infectious diseases always pose a threat to humans along with plant and animal
life. SARS-CoV2 is the recently emerged viral infection that originated from Wuhan city of the …

Sepsis is associated with a high risk of death, and the crosstalk between gut microbiota and
sepsis is gradually revealed. Indole 3-propionic acid (IPA) is a gut microbiota-derived …

The evolutionary and genetic origins of the specialized body plan of flatfish are largely
unclear. We analyzed the genomes of 11 flatfish species representing 9 of the 14 …

N6-methyladenosine (m6A) RNA modification is a fundamental determinant of mRNA
metabolism in eukaryotic cells and is involved in numerous physiological and pathological …

RELMα is a small, secreted protein expressed by type 2 cytokine-activated “M2”
macrophages in helminth infection and allergy. At steady state and in response to type 2 …

Growth differentiation factor 15 (GDF15) is involved in the occurrence and development of
many diseases, and there are few studies on its relationship with sepsis. This article aims to …