Detecting balancing selection in genomes: limits and prospects
In spite of the long‐term interest in the process of balancing selection, its frequency in
genomes and evolutionary significance remain unclear due to challenges related to its …
genomes and evolutionary significance remain unclear due to challenges related to its …
Immunity, resistance and tolerance in bird–parasite interactions
G Sorci - Parasite immunology, 2013 - Wiley Online Library
Interacting pathogens and hosts have evolved reciprocal adaptations whose function is to
allow host exploitation (from the pathogen stand point) or minimize the cost of infection (from …
allow host exploitation (from the pathogen stand point) or minimize the cost of infection (from …
amplisas: a web server for multilocus genoty** using next‐generation amplicon sequencing data
Next‐generation sequencing (NGS) technologies are revolutionizing the fields of biology
and medicine as powerful tools for amplicon sequencing (AS). Using combinations of …
and medicine as powerful tools for amplicon sequencing (AS). Using combinations of …
Evolution of copy number at the MHC varies across the avian tree of life
The evolution of the major histocompatibility complex (MHC) is shaped by frequent gene
duplications and deletions, which generate extensive variation in the number of loci (gene …
duplications and deletions, which generate extensive variation in the number of loci (gene …
Mhc supertypes confer both qualitative and quantitative resistance to avian malaria infections in a wild bird population
Major histocompatibility complex (Mhc) genes are believed to play a key role in the genetic
basis of disease control. Although numerous studies have sought links between Mhc and …
basis of disease control. Although numerous studies have sought links between Mhc and …
Major histocompatibility complex class I diversity limits the repertoire of T cell receptors
Major histocompatibility complex (MHC) genes encode proteins that initiate adaptive
immune responses through the presentation of foreign antigens to T cells. The high …
immune responses through the presentation of foreign antigens to T cells. The high …
MHC variation is related to a sexually selected ornament, survival, and parasite resistance in common yellowthroats
Hamilton and Zuk proposed that females choose mates based on ornaments whose
expression is dependent on their genetically based resistance to parasites. The major …
expression is dependent on their genetically based resistance to parasites. The major …
The genomic architecture of the passerine MHC region: High repeat content and contrasting evolutionary histories of single copy and tandemly duplicated MHC genes
The major histocompatibility complex (MHC) is of central importance to the immune system,
and an optimal MHC diversity is believed to maximize pathogen elimination. Birds show …
and an optimal MHC diversity is believed to maximize pathogen elimination. Birds show …
Avian MHC evolution in the era of genomics: phase 1.0
Birds are a wonderfully diverse and accessible clade with an exceptional range of ecologies
and behaviors, making the study of the avian major histocompatibility complex (MHC) of …
and behaviors, making the study of the avian major histocompatibility complex (MHC) of …
Extreme MHC class I diversity in the sedge warbler (Acrocephalus schoenobaenus); selection patterns and allelic divergence suggest that different genes have …
Background Recent work suggests that gene duplications may play an important role in the
evolution of immunity genes. Passerine birds, and in particular Sylvioidea warblers, have …
evolution of immunity genes. Passerine birds, and in particular Sylvioidea warblers, have …