The Hippo pathway plays a critical role for balancing proliferation and differentiation, thus
regulating tissue homeostasis. The pathway acts through a kinase cascade whose final …

During oncogenesis, cells become unrestrictedly proliferative thereby altering the tissue
homeostasis and resulting in subsequent hyperplasia. This process is paralleled by …

Ferroptosis is an iron‐dependent mode of non‐apoptotic cell death characterized by
accumulation of lipid reactive oxygen species (ROS). As a regulator of ROS, cytoglobin …

Simple Summary Although great breakthroughs have been made in cancer treatment
following the development of targeted therapy and immune therapy, resistance against anti …

Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC).
PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are …

The advancement of new therapies, including targeted therapies and immunotherapies, has
improved the survival of non-small-cell lung cancer (NSCLC) patients in the last decade …

Inflammatory bowel disease (IBD) is a disorder, which involves the gastrointestinal (GI) tract
consisting Crohn's disease (CD) and ulcerative colitis (UC). The etiology of this disease is …

The Hippo pathway plays an important role in cell proliferation, apoptosis, and
differentiation; it is a crucial regulatory pathway in organ development and tumor growth …

Colorectal cancer (CRC) is the third most common malignant tumor in the world. CRC has
high morbidity and mortality rates and it is a serious threat to human health. Ferroptosis is a …

Background Hepatocellular carcinoma (HCC) remains a major global health burden due to
its high prevalence and mortality. Emerging evidence reveals that microRNA (miRNA) plays …