Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal
feature of astrocytes is their complex and visually enchanting morphology, referred to as …

Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

Understanding the complexity of cellular function within a tissue necessitates the
combination of multiple phenotypic readouts. Here, we developed a method that links …

Neuron-glia interactions play a critical role in the regulation of synapse formation and circuit
assembly. Here we demonstrate that canonical Sonic hedgehog (Shh) pathway signaling in …

Persistent activity in populations of neurons, time-varying activity across a neural population,
or activity-silent mechanisms carried out by hidden internal states of the neural population …

The glial cells astrocytes have long been recognized as important neuron-supporting
elements in brain development, homeostasis, and metabolism. After the discovery that the …

Unraveling the fine structure of the brain is important to provide a better understanding of its
normal and abnormal functioning. Application of high-resolution electron microscopic …

Microglia, the resident macrophage cells of the central nervous system (CNS), are involved
in a myriad of processes required to maintain CNS homeostasis. These cells are dynamic …

Astrocytes are the most numerous type of neuroglia in the brain and have a predominant
influence on the cerebrovascular system; they control perivascular homeostasis, the integrity …