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[HTML][HTML] Signatures of mitochondrial dysfunction and impaired fatty acid metabolism in plasma of patients with post-acute sequelae of COVID-19 (PASC)
Exercise intolerance is a major manifestation of post-acute sequelae of severe acute
respiratory syndrome coronavirus infection (PASC, or “long-COVID”). Exercise intolerance in …
respiratory syndrome coronavirus infection (PASC, or “long-COVID”). Exercise intolerance in …
COVID‐19 metabolism: Mechanisms and therapeutic targets
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) dysregulates antiviral
signaling, immune response, and cell metabolism in human body. Viral genome and …
signaling, immune response, and cell metabolism in human body. Viral genome and …
The roles of the kynurenine pathway in COVID-19 neuropathogenesis
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent
of the highly contagious respiratory disease Corona Virus Disease 2019 (COVID-19) that …
of the highly contagious respiratory disease Corona Virus Disease 2019 (COVID-19) that …
The role of Coinhibitory receptors in B cell dysregulation in SARS-CoV-2–infected individuals with severe disease
Severe SARS-CoV-2 infection is associated with significant immune dysregulation involving
different immune cell subsets. In this study, when analyzing critically ill COVID-19 patients …
different immune cell subsets. In this study, when analyzing critically ill COVID-19 patients …
Metabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation
Background metabolic changes through SARS-CoV-2 infection has been reported but not
fully comprehended. This metabolic dysregulation affects multiple organs during COVID-19 …
fully comprehended. This metabolic dysregulation affects multiple organs during COVID-19 …
Significance of nitrosative stress and glycoxidation products in the diagnosis of COVID-19
Nitrosative stress promotes protein glycoxidation, and both processes can occur during an
infection with the SARS-CoV-2 virus. Therefore, the aim of this study was to assess selected …
infection with the SARS-CoV-2 virus. Therefore, the aim of this study was to assess selected …
The Biology and Biochemistry of Kynurenic Acid, a Potential Nutraceutical with Multiple Biological Effects
Kynurenic acid (KYNA) is an antioxidant degradation product of tryptophan that has been
shown to have a variety of cytoprotective, neuroprotective and neuronal signalling …
shown to have a variety of cytoprotective, neuroprotective and neuronal signalling …
[HTML][HTML] Integrative plasma metabolic and lipidomic modelling of SARS-CoV-2 infection in relation to clinical severity and early mortality prediction
An integrative multi-modal metabolic phenoty** model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
Plasma metabolomics profiling identifies new predictive biomarkers for disease severity in COVID-19 patients
Recently, numerous studies have reported on different predictive models of disease severity
in COVID-19 patients. Herein, we propose a highly predictive model of disease severity by …
in COVID-19 patients. Herein, we propose a highly predictive model of disease severity by …
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model
Over the last century, outbreaks and pandemics have occurred with disturbing regularity,
necessitating advance preparation and large-scale, coordinated response. Here, we …
necessitating advance preparation and large-scale, coordinated response. Here, we …