A global view of hepatocellular carcinoma: trends, risk, prevention and management

JD Yang, P Hainaut, GJ Gores, A Amadou… - Nature reviews …, 2019 - nature.com
Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death
worldwide. Risk factors for HCC include chronic hepatitis B and hepatitis C, alcohol …

Biomarker development for hepatocellular carcinoma early detection: current and future perspectives

S Sengupta, ND Parikh - Hepatic oncology, 2017 - Taylor & Francis
Early detection of hepatocellular carcinoma (HCC) leads to improved survival; however,
current early detection strategies for HCC surveillance are ineffective. Thus, there has been …

GALAD score for hepatocellular carcinoma detection in comparison with liver ultrasound and proposal of GALADUS score

JD Yang, BD Addissie, KC Mara, WS Harmsen… - … Biomarkers & Prevention, 2019 - AACR
Background: The GALAD score is a serum biomarker–based model that predicts the
probability of having hepatocellular carcinoma (HCC) in patients with chronic liver disease …

[HTML][HTML] Real-world data on the diagnosis, treatment, and management of hepatocellular carcinoma in the Asia-Pacific: the INSIGHT study

YK Sim, MC Chong, M Gandhi, YM Pokharkar, Y Zhu… - Liver Cancer, 2024 - karger.com
Introduction: Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed cancer
and the third leading cause of cancer death worldwide. While there has been rapid evolution …

Improving B-mode ultrasound diagnostic performance for focal liver lesions using deep learning: A multicentre study

Q Yang, J Wei, X Hao, D Kong, X Yu, T Jiang, J **… - …, 2020 - thelancet.com
Background The diagnosis performance of B-mode ultrasound (US) for focal liver lesions
(FLLs) is relatively limited. We aimed to develop a deep convolutional neural network of US …

A high-throughput test enables specific detection of hepatocellular carcinoma

D Cheishvili, C Wong, MM Karim, MG Kibria… - Nature …, 2023 - nature.com
High-throughput tests for early cancer detection can revolutionize public health and reduce
cancer morbidity and mortality. Here we show a DNA methylation signature for …

Diagnostic per-patient accuracy of an abbreviated hepatobiliary phase gadoxetic acid–enhanced MRI for hepatocellular carcinoma surveillance

RM Marks, A Ryan, ER Heba, A Tang… - American Journal of …, 2015 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study is to evaluate the per-patient diagnostic performance
of an abbreviated gadoxetic acid–enhanced MRI protocol for hepatocellular carcinoma …

Imaging outcomes of liver imaging reporting and data system version 2014 category 2, 3, and 4 observations detected at CT and MR imaging

M Tanabe, A Kanki, T Wolfson, EAC Costa… - Radiology, 2016 - pubs.rsna.org
Purpose To determine the proportion of untreated Liver Imaging Reporting and Data System
(LI-RADS) version 2014 category 2, 3, and 4 observations that progress, remain stable, or …

Diagnostic per-lesion performance of a simulated gadoxetate disodium-enhanced abbreviated MRI protocol for hepatocellular carcinoma screening

BG Tillman, JD Gorman, JM Hru, MH Lee, MC King… - Clinical radiology, 2018 - Elsevier
Aim To evaluate the diagnostic per-lesion performance of a simulated gadoxetate disodium-
enhanced abbreviated MRI (AMRI) in cirrhotic and chronic hepatitis B (CHB) patients for …

Consensus statements from a multidisciplinary expert panel on the utilization and application of a liver-specific MRI contrast agent (gadoxetic acid)

K Jhaveri, S Cleary, P Audet, F Balaa… - American Journal of …, 2015 - Am Roentgen Ray Soc
OBJECTIVE. This systematic review presents evidence-based consensus statements as
reported by a multidisciplinary expert panel (six abdominal radiologists, four hepatobiliary …