Transforming growth factor β (TGF-β) has long been identified with its intensive involvement
in early embryonic development and organogenesis, immune supervision, tissue repair, and …

TGFβ signalling has key roles in cancer progression: most carcinoma cells have inactivated
their epithelial antiproliferative response and benefit from increased TGFβ expression and …

Transforming growth factor β (TGF-β) is a secreted cytokine that regulates cell proliferation,
migration, and the differentiation of a plethora of different cell types. Consistent with these …

Transforming growth factor-β (TGFβ) family members are structurally and functionally related
cytokines that have diverse effects on the regulation of cell fate during embryonic …

Genetic alterations affecting transforming growth factor–β (TGF-β) signaling are
exceptionally common in diseases and cancers of the gastrointestinal system. As a regulator …

Hepatocellular carcinoma (HCC) is an inflammation-induced and chemotherapy-resistant
cancer. Dysregulated signaling in the transforming growth factor beta (TGF-β) pathway plays …

The genetic mutations that contribute to the transformation of healthy cells into cancerous
cells have been the subject of extensive research. The molecular aberrations that lead to …

Background In the current treatment of non-small cell lung cancer (NSCLC), traditional
chemotherapy causes high toxicity, so it is necessary to develop safe chemical drug delivery …

Transforming growth factor (TGF)-β is a secreted multifunctional cytokine that signals via
plasma membrane TGF-β type I and type II receptors and intercellular SMAD transcriptional …

Aims The dysregulation of TGF‐β signaling is a crucial pathophysiological process in
tumorigenesis and progression. LncRNAs have diverse biological functions and are …