Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer

Z Zeng, M Fu, Y Hu, Y Wei, X Wei, M Luo - Molecular Cancer, 2023 - Springer
Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …

Clinical utility of circulating non-coding RNAs—an update

S Anfossi, A Babayan, K Pantel, GA Calin - Nature reviews Clinical …, 2018 - nature.com
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …

[HTML][HTML] Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19

J Ren, L Ding, D Zhang, G Shi, Q Xu, S Shen… - Theranostics, 2018 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …

[HTML][HTML] LncRNA H19: A novel oncogene in multiple cancers

J Yang, M Qi, X Fei, X Wang, K Wang - International journal of …, 2021 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are a series of non-coding RNAs that lack open reading
frameworks. Accumulating evidence suggests important roles for lncRNAs in various …

LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury

P Wan, W Su, Y Zhang, Z Li, C Deng, J Li… - Cell Death & …, 2020 - nature.com
Abstract Ischemia-reperfusion (I/R) is a common pathology when the blood supply to an
organ was disrupted and then restored. During the reperfusion process, inflammation and …

Non-coding RNAs in GI cancers: from cancer hallmarks to clinical utility

MP Dragomir, S Kopetz, JA Ajani, GA Calin - Gut, 2020 - gut.bmj.com
One of the most unexpected discoveries in molecular oncology, in the last decades, was the
identification of a new layer of protein coding gene regulation by transcripts that do not …

Long non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy

M Wang, D Han, Z Yuan, H Hu, Z Zhao, R Yang… - Cell death & …, 2018 - nature.com
Chemotherapy failure is the major cause of recurrence and poor prognosis in colorectal
cancer (CRC) patients. The role of the differentially expressed lncRNAs in 5-Fluorouracil …

[HTML][HTML] MicroRNA-567 inhibits cell proliferation and induces cell apoptosis in A549 NSCLC cells by regulating cyclin-dependent kinase 8

MA Elkady, AS Doghish, A Elshafei… - Saudi Journal of …, 2021 - Elsevier
Abstract MicroRNA-567 (miR-567) plays a decisive role in cancers whereas its role in non-
small cell lung cancer (NSCLC) is still unexplored. This study was therefore planned to …

Emerging role of oncogenic long noncoding RNA as cancer biomarkers

M Aprile, V Costa, A Cimmino… - International journal of …, 2023 - Wiley Online Library
The view of long noncoding RNAs as nonfunctional “garbage” has been definitely outdated
by the large body of evidence indicating this class of ncRNAs as “golden junk”, especially in …

Non-coding RNA in bladder cancer

Y Li, G Li, X Guo, H Yao, G Wang, C Li - Cancer letters, 2020 - Elsevier
Bladder cancer is the tenth most common cancer worldwide and has been associated with
high mortality and morbidity. Although the treatment of bladder cancer is based on well …