The gut microbiota changes with age, but it is not clear to what degree these changes are
due to physiologic changes, age-associated inflammation or immunosenescence, diet …

Background It is a well-described clinical phenomenon that females live longer than males,
yet tend to experience greater levels of co-morbidity and disability. Females can therefore be …

Background The risk of severe COVID-19 if an individual becomes infected is known to be
higher in older individuals and those with underlying health conditions. Understanding the …

Objectives To operationalize frailty using eight scales and to compare their content validity,
feasibility, prevalence estimates of frailty, and ability to predict all‐cause mortality. Design …

The aging process in an older adult is driven by multi-dimensional inputs that contribute to
the individual's overall progressive decline and ultimately death. These inputs span from …

Demonstrations that grip strength has predictive power in relation to a range of health
conditions—even when these are assessed decades later—has motivated claims that hand …

Frailty can be viewed as a state of physiological decline that increases susceptibility to
adverse health outcomes. This loss of physiological reserve means that even small stressors …

Background Frailty renders older individuals more prone to adverse health outcomes. Little
has been reported about the transitions between the different frailty states. We attempted to …

Aim In the present study, we aimed to update the data of frailty status in the European
community‐dwelling population of older adults, based on the latest data released (wave 6) …

Background Physical frailty is a common characteristic of older people with the ageing
process and has been viewed as a major public health issue. The longitudinal association …