The genetic causes of convergent evolution

DL Stern - Nature Reviews Genetics, 2013 - nature.com
The evolution of phenotypic similarities between species, known as convergence, illustrates
that populations can respond predictably to ecological challenges. Convergence often …

Adaptive laboratory evolution–principles and applications for biotechnology

M Dragosits, D Mattanovich - Microbial cell factories, 2013 - Springer
Adaptive laboratory evolution is a frequent method in biological studies to gain insights into
the basic mechanisms of molecular evolution and adaptive changes that accumulate in …

Clinically relevant mutations in core metabolic genes confer antibiotic resistance

AJ Lopatkin, SC Bening, AL Manson, JM Stokes… - Science, 2021 - science.org
Although metabolism plays an active role in antibiotic lethality, antibiotic resistance is
generally associated with drug target modification, enzymatic inactivation, and/or transport …

[書籍][B] Eco-evolutionary dynamics

AP Hendry - 2017 - degruyter.com
In recent years, scientists have realized that evolution can occur on timescales much shorter
than the" long lapse of ages" emphasized by Darwin—in fact, evolutionary change is …

Altered sterol composition renders yeast thermotolerant

L Caspeta, Y Chen, P Ghiaci, A Feizi, S Buskov… - Science, 2014 - science.org
Ethanol production for use as a biofuel is mainly achieved through simultaneous
saccharification and fermentation by yeast. Operating at≥ 40° C would be beneficial in …

Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

GI Lang, DP Rice, MJ Hickman, E Sodergren… - Nature, 2013 - nature.com
The dynamics of adaptation determine which mutations fix in a population, and hence how
reproducible evolution will be. This is central to understanding the spectra of mutations …

Random mutagenesis as a promising tool for microalgal strain improvement towards industrial production

M Trovão, LM Schüler, A Machado, G Bombo… - Marine drugs, 2022 - mdpi.com
Microalgae have become a promising novel and sustainable feedstock for meeting the rising
demand for food and feed. However, microalgae-based products are currently hindered by …

Development of a comprehensive genotype-to-fitness map of adaptation-driving mutations in yeast

S Venkataram, B Dunn, Y Li, A Agarwala, J Chang… - Cell, 2016 - cell.com
Adaptive evolution plays a large role in generating the phenotypic diversity observed in
nature, yet current methods are impractical for characterizing the molecular basis and fitness …

Evolution in the light of fitness landscape theory

I Fragata, A Blanckaert, MAD Louro, DA Liberles… - Trends in ecology & …, 2019 - cell.com
By formalizing the relationship between genotype or phenotype and fitness, fitness
landscapes harbor information on molecular and evolutionary constraints. The shape of the …

Experimental evolution in biofilm populations

HP Steenackers, I Parijs, KR Foster… - FEMS microbiology …, 2016 - academic.oup.com
Biofilms are a major form of microbial life in which cells form dense surface associated
communities that can persist for many generations. The long-life of biofilm communities …