Coronaviruses are enveloped positive-stranded RNA viruses that replicate in the cytoplasm.
To deliver their nucleocapsid into the host cell, they rely on the fusion of their envelope with …

The emerging and re-emerging viral diseases are continuous threats to the wellbeing of
human life. Previous outbreaks of Severe Acute Respiratory Syndrome (SARS) and Middle …

Many viral fusion proteins are primed by proteolytic cleavage near their fusion peptides.
While the coronavirus (CoV) spike (S) protein is known to be cleaved at the S1/S2 boundary …

Viral membrane fusion is an orchestrated process triggered by membrane-anchored viral
fusion glycoproteins. The S2 subunit of the spike glycoprotein from severe acute respiratory …

Fusion peptides (FP) are prominent hydrophobic segments of viral fusion proteins that play
critical roles in viral entry. FPs interact with and insert into the host lipid membranes …

Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) poses a serious
public health hazard. The S2 subunit of the S glycoprotein of SARS-CoV carries out fusion …

The receptor binding domain (RBD) of spike proteins plays a crucial role in the process of
severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) attachment to the human …

In order to complete the fusion process of SARS-CoV virus, several regions of the S2 virus
envelope glycoprotein are necessary. Recent studies have identified three membrane-active …

In the present work we have analyzed the effect of StAsp-PSI (plant-specific insert of potato
aspartic protease) on the structural and thermotropic properties of the major phospholipid …

The SARS coronavirus (SARS-CoV) envelope spike (S) glycoprotein, a Class I viral fusion
protein, is responsible for the fusion between the membranes of the virus and the target cell …