Cyclooxygenases play a vital role in inflammation and are responsible for the production of
prostaglandins. Two cyclooxygenases are described, the constitutive cyclooxygenase-1 and …

Cyclooxygenase-2 is a very important physiological enzyme playing key roles in various
biological functions especially in the mechanism of pain and inflammation, among other …

Abstract Development in the area of acceptorless dehydrogenation (AD) and borrowing
hydrogen (BH) catalysis emerge as one of the potential tools for various C− C and C …

Benzoxazole is an attractive scaffold in medicinal chemistry due to its diverse biological
applications. From 2016 to 2023, a plethora of benzoxazole derivatives have been …

Herein, we have carried out a structural optimization campaign to discover the novel anti-
tumor agents with our previously screened YQY-26 as the hit compound. A library of thirty …

Introduction Epidermal growth factor receptor (EGFR) inhibition is an imperative therapeutic
approach targeting various types of cancer including colorectal, lung, breast, and pancreatic …

The presence of benzoxazole moiety in most of the heterocyclic compounds is well reported.
The present literature review mainly highlights the novel synthetic transformation and …

Background: This review elaborates the updated synthetic and pharmacological approaches
of a known group of dihydropyrimidinones/thiones from the multi-component reaction like …

To explore the structure-property relationship in a set of molecules against Cyclooxygenase-
2 (COX-2), pharmacophore modeling, molecular docking and 3D-QSAR studies were …

A simple, economical and metal-free approach to the synthesis of 2-substituted
benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols …