Mechanisms of drug resistance: quinolone resistance
DC Hooper, GA Jacoby - Annals of the New York academy of …, 2015 - Wiley Online Library
Quinolone antimicrobials are synthetic and widely used in clinical medicine. Resistance
emerged with clinical use and became common in some bacterial pathogens. Mechanisms …
emerged with clinical use and became common in some bacterial pathogens. Mechanisms …
Plasmid‐mediated quinolone resistance
GA Jacoby, J Strahilevitz… - Plasmids: Biology and …, 2015 - Wiley Online Library
Plasmid‐mediated quinolone resistance (PMQR) was late in being discovered. Nalidixic
acid, the first quinolone to be used clinically, was introduced in 1967 for urinary tract …
acid, the first quinolone to be used clinically, was introduced in 1967 for urinary tract …
Plasmid-mediated quinolone resistance: two decades on
After two decades of the discovery of plasmid-mediated quinolone resistance (PMQR), three
different mechanisms have been associated to this phenomenon: target protection (Qnr …
different mechanisms have been associated to this phenomenon: target protection (Qnr …
CrpP is a novel ciprofloxacin-modifying enzyme encoded by the Pseudomonas aeruginosa pUM505 plasmid
VM Chávez-Jacobo… - Antimicrobial agents …, 2018 - Am Soc Microbiol
The pUM505 plasmid, isolated from a clinical Pseudomonas aeruginosa isolate, confers
resistance to ciprofloxacin (CIP) when transferred into the standard P. aeruginosa strain …
resistance to ciprofloxacin (CIP) when transferred into the standard P. aeruginosa strain …
Prevalence and fate of carbapenemase genes in a wastewater treatment plant in northern China
Carbapenemase-producing strains of bacteria, which were primarily found in the medical
field, have increasingly been found in the environment, thus posing potential risks to public …
field, have increasingly been found in the environment, thus posing potential risks to public …
Characterization of Plasmid-Mediated Quinolone Resistance (PMQR) Genes in Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Pediatric Clinical …
This work describes the characterization of plasmid-mediated quinolone-resistance (PMQR)
genes from a multicenter study of ESBL-producing Enterobacteriaceae pediatric clinical …
genes from a multicenter study of ESBL-producing Enterobacteriaceae pediatric clinical …
Isolation of carbapenem-resistant NDM-1-positive Providencia rettgeri in Mexico
Isolation of carbapenem-resistant NDM-1-positive Providencia rettgeri in Mexico was found
as part of the 10 kb Tn3-like element Tn4401, PCR assays with specific primers for Tn4401 …
as part of the 10 kb Tn3-like element Tn4401, PCR assays with specific primers for Tn4401 …
Prevalence of the crpP gene conferring decreased ciprofloxacin susceptibility in enterobacterial clinical isolates from Mexican hospitals
VM Chávez-Jacobo… - Journal of …, 2019 - academic.oup.com
Objectives This study investigated the presence of the crpP gene, which encodes an
enzymatic mechanism of antibiotic phosphorylation that decreases ciprofloxacin …
enzymatic mechanism of antibiotic phosphorylation that decreases ciprofloxacin …
Plasmid analysis of NDM metallo-β-lactamase-producing Enterobacterales isolated in Vietnam
Carbapenem-resistant Enterobacterales (CRE) represent a serious threat to public health
due to the lack of treatment and high mortality. The rate of antimicrobial resistance of …
due to the lack of treatment and high mortality. The rate of antimicrobial resistance of …
Plasmids and genes contributing to high-level quinolone resistance in Escherichia coli
Introduction: The importance of plasmid-mediated quinolone resistance (PMQR) in
Enterobacterales and its high incidence has been emphasised many times. However, a …
Enterobacterales and its high incidence has been emphasised many times. However, a …