Gut dysbiosis, defective autophagy and altered immune responses in neurodegenerative diseases: Tales of a vicious cycle

SB Chidambaram, MM Essa, AG Rathipriya… - Pharmacology & …, 2022 - Elsevier
The human microbiota comprises trillions of symbiotic microorganisms and is involved in
regulating gastrointestinal (GI), immune, nervous system and metabolic homeostasis …

Crosstalk between gut and brain in Alzheimer's disease: the role of gut microbiota modulation strategies

U Shabbir, MS Arshad, A Sameen, DH Oh - Nutrients, 2021 - mdpi.com
The gut microbiota (GM) represents a diverse and dynamic population of microorganisms
and about 100 trillion symbiotic microbial cells that dwell in the gastrointestinal tract. Studies …

Genetic correlations between Alzheimer's disease and gut microbiome genera

D Cammann, Y Lu, MJ Cummings, ML Zhang… - Scientific Reports, 2023 - nature.com
A growing body of evidence suggests that dysbiosis of the human gut microbiota is
associated with neurodegenerative diseases like Alzheimer's disease (AD) via …

Neuroinflammation and the gut microbiota: possible alternative therapeutic targets to counteract Alzheimer's disease?

M Cerovic, G Forloni, C Balducci - Frontiers in aging neuroscience, 2019 - frontiersin.org
Alzheimer's disease (AD) is a complex, multi-factorial disease affecting various brain
systems. This complexity implies that successful therapies must be directed against several …

Protective effect of anthocyanins against neurodegenerative diseases through the microbial-intestinal-brain axis: A critical review

H Zhong, J Xu, M Yang, M Hussain, X Liu, F Feng… - Nutrients, 2023 - mdpi.com
With the increase in human mean age, the prevalence of neurodegenerative diseases (NDs)
also rises. This negatively affects mental and physiological health. In recent years, evidence …

The role of microbiome-host interactions in the development of Alzheimer´ s disease

C Weber, A Dilthey, P Finzer - Frontiers in cellular and infection …, 2023 - frontiersin.org
Alzheimers disease (AD) is the most prevalent cause of dementia. It is often assumed that
AD is caused by an aggregation of extracellular beta-amyloid and intracellular tau-protein …

Food, gut barrier dysfunction, and related diseases: A new target for future individualized disease prevention and management

L Liang, C Saunders, N Sanossian - Food science & nutrition, 2023 - Wiley Online Library
Dysfunction of gut barrier is known as “leaky gut” or increased intestinal permeability.
Numerous recent scientific evidences showed the association between gut dysfunction and …

Interactions between systemic diseases and oral microbiota shifts in the aging community: A narrative review

SA Mosaddad, P Mahootchi, S Safari… - Journal of Basic …, 2023 - Wiley Online Library
As a gateway to general health and a diverse microbial habitat, the oral cavity is colonized
by numerous microorganisms such as bacteria, fungi, viruses, and archaea. Oral microbiota …

Gut microbiota is an impact factor based on the brain-gut axis to alzheimer's disease: A systematic review

B Zou, J Li, RX Ma, XY Cheng, RY Ma… - Aging and …, 2023 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a degenerative disease of the central nervous system. The
pathogenesis of AD has been explained using cholinergic, β-amyloid toxicity, tau protein …

[HTML][HTML] Gut microbiota, its role in induction of Alzheimer's disease pathology, and possible therapeutic interventions: special focus on anthocyanins

MS Khan, M Ikram, JS Park, TJ Park, MO Kim - Cells, 2020 - mdpi.com
The human gut is a safe environment for several microbes that are symbiotic and important
for the wellbeing of human health. However, studies on gut microbiota in different animals …