Theory and simulation of the ultrafast double-bond isomerization of biological chromophores

S Gozem, HL Luk, I Schapiro, M Olivucci - Chemical reviews, 2017 - ACS Publications
Ultrafast processes in light-absorbing proteins have been implicated in the primary step in
the light-to-energy conversion and the initialization of photoresponsive biological functions …

Blue-light receptors for optogenetics

A Losi, KH Gardner, A Möglich - Chemical reviews, 2018 - ACS Publications
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …

Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein

K Pande, CDM Hutchison, G Groenhof, A Aquila… - Science, 2016 - science.org
A variety of organisms have evolved mechanisms to detect and respond to light, in which the
response is mediated by protein structural changes after photon absorption. The initial step …

Optical control of ultrafast structural dynamics in a fluorescent protein

CDM Hutchison, JM Baxter, A Fitzpatrick, G Dorlhiac… - Nature …, 2023 - nature.com
The photoisomerization reaction of a fluorescent protein chromophore occurs on the ultrafast
timescale. The structural dynamics that result from femtosecond optical excitation have …

Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein

J Tenboer, S Basu, N Zatsepin, K Pande… - Science, 2014 - science.org
Serial femtosecond crystallography using ultrashort pulses from x-ray free electron lasers
(XFELs) enables studies of the light-triggered dynamics of biomolecules. We used …
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P Naumov, SC Sahoo, BA Zakharov… - Angewandte …, 2013 - Wiley Online Library
During the process of evolution, animals and plants have naturally acquired two capabilities
that are of critical importance for their survival: to evolve and to disperse. Natural motility is a …

Time-resolved serial femtosecond crystallography at the European XFEL

S Pandey, R Bean, T Sato, I Poudyal, J Bielecki… - Nature …, 2020 - nature.com
Abstract The European XFEL (EuXFEL) is a 3.4-km long X-ray source, which produces
femtosecond, ultrabrilliant and spatially coherent X-ray pulses at megahertz (MHz) repetition …

[图书][B] 4D electron microscopy: imaging in space and time

AH Zewail, JM Thomas - 2009 - books.google.com
The modern electron microscope, as a result of recent revolutionary developments and
many evolutionary ones, now yields a wealth of quantitative knowledge pertaining to …

N- and C-Terminal Flanking Regions Modulate Light-Induced Signal Transduction in the LOV2 Domain of the Blue Light Sensor Phototropin 1 from Avena sativa,

AS Halavaty, K Moffat - Biochemistry, 2007 - ACS Publications
Light sensing by photoreceptors controls phototropism, chloroplast movement, stomatal
opening, and leaf expansion in plants. Understanding the molecular mechanism by which …