Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity
H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …
structure and functional design that leverages on material engineering to modulate its …
Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions
P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …
Engineered hydrogels for mechanobiology
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …
Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment
Z Li, Y Ding, J Liu, J Wang, F Mo, Y Wang… - Nature …, 2022 - nature.com
Immunosuppressive cells residing in the tumor microenvironment, especially tumor
associated macrophages (TAMs), hinder the infiltration and activation of T cells, limiting the …
associated macrophages (TAMs), hinder the infiltration and activation of T cells, limiting the …
Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles
Nanomedicine holds promise to enhance cancer immunotherapy; however, its potential to
elicit highly specific anti-tumor immunity without compromising immune tolerance has yet to …
elicit highly specific anti-tumor immunity without compromising immune tolerance has yet to …
Biomedical polymers: synthesis, properties, and applications
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors
Adoptive cell therapy (ACT) has proven to be highly effective in treating blood cancers, but
traditional approaches to ACT are poorly effective in treating solid tumors observed …
traditional approaches to ACT are poorly effective in treating solid tumors observed …
Boosting checkpoint immunotherapy with biomaterials
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
Amplification of activated near-infrared afterglow luminescence by introducing twisted molecular geometry for understanding neutrophil-involved diseases
Understanding the mechanism and progression of neutrophil-involved diseases (eg, acute
inflammation) is of great importance. However, current available analytical methods neither …
inflammation) is of great importance. However, current available analytical methods neither …
Recent advances in overcoming barriers to cell‐based delivery systems for cancer immunotherapy
Y Ding, Y Wang, Q Hu - Exploration, 2022 - Wiley Online Library
Immunotherapy strategies that use cell‐based delivery systems have sparked much interest
in the treatment of malignancies, owing to their high biocompatibility, excellent tumor …
in the treatment of malignancies, owing to their high biocompatibility, excellent tumor …