Persistent coxsackievirus infection: enterovirus persistence in chronic myocarditis and dilated cardiomyopathy

NM Chapman, KS Kim - Group B Coxsackieviruses, 2008 - Springer
Enteroviral infection of the heart has been noted in a significant proportion of cases of
myocarditis and dilated cardiomyopathy. The presence of enterovirus RNA at stages of …

Coxsackievirus B3—its potential as an oncolytic virus

A Geisler, A Hazini, L Heimann, J Kurreck, H Fechner - Viruses, 2021 - mdpi.com
Oncolytic virotherapy represents one of the most advanced strategies to treat otherwise
untreatable types of cancer. Despite encouraging developments in recent years, the limited …

Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells

P Ylipaasto, K Klingel, AM Lindberg, T Otonkoski… - Diabetologia, 2004 - Springer
Aims/hypothesis It is thought that enterovirus infections cause beta-cell damage and
contribute to the development of Type 1 diabetes by replicating in the pancreatic islets. We …

Coxsackievirus myocarditis: interplay between virus and host in the pathogenesis of heart disease

PE Tam - Viral immunology, 2006 - liebertpub.com
Coxsackievirus (CVB) infection is a significant cause of myocarditis and dilated
cardiomyopathy (DCM). Heart disease may be caused by direct cytopathic effects of the …

Viral myocarditis and dilated cardiomyopathy: etiology and pathogenesis

SA Huber - Current Pharmaceutical Design, 2016 - ingentaconnect.com
Myocarditis is an inflammation of the myocardium which often follows microbial infections
and is a significant cause of sudden unexpected death in the young (< 40 years of age) and …

Vaccines against group B coxsackieviruses and their importance

K Mone, N Lasrado, M Sur, J Reddy - Vaccines, 2023 - mdpi.com
The group B coxsackieviruses (CVBs) exist in six serotypes (CVB1 to CVB6). Disease
associations have been reported for most serotypes, and multiple serotypes can cause …

Infectious entry pathway of enterovirus B species

V Marjomäki, P Turkki, M Huttunen - Viruses, 2015 - mdpi.com
Enterovirus B species (EV-B) are responsible for a vast number of mild and serious acute
infections. They are also suspected of remaining in the body, where they cause persistent …

Heparan sulfates and coxsackievirus-adenovirus receptor: each one mediates coxsackievirus B3 PD infection

AE Zautner, U Korner, A Henke, C Badorff… - Journal of …, 2003 - Am Soc Microbiol
Amino acid exchanges in the virus capsid protein VP1 allow the coxsackievirus B3 variant
PD (CVB3 PD) to replicate in decay accelerating factor (DAF)-negative and coxsackievirus …

Enterovirus persistence as a mechanism in the pathogenesis of type 1 diabetes

EK Alid**ou, F Sane, I Engelmann, V Geenen… - Discovery …, 2014 - orbi.uliege.be
Beyond acute clinical conditions, the role of enteroviruses (EVs) in chronic human diseases
has been described. Although they are considered as highly cytolytic viruses, EVs can …

Persistence of coxsackievirus B4 in pancreatic β cells disturbs insulin maturation, pattern of cellular proteins, and DNA methylation

MP Nekoua, A Bertin, F Sane, JP Gimeno, I Fournier… - Microorganisms, 2021 - mdpi.com
Coxsackievirus-B4 (CV-B4) can persist in pancreatic cell lines and impair the phenoytpe
and/or gene expressions in these cells; however, the models used to study this …