Innate lymphoid cells: major players in inflammatory diseases

M Ebbo, A Crinier, F Vély, E Vivier - Nature Reviews Immunology, 2017‏ - nature.com
Recent years have seen a marked increase in our understanding of innate lymphoid cells
(ILCs). ILCs can be classified into different groups based on their similarity to T cell subsets …

Current genetic landscape in common variable immune deficiency

H Abolhassani, L Hammarström… - Blood, The Journal …, 2020‏ - ashpublications.org
Using whole-exome sequencing to examine the genetic causes of immune deficiency in 235
common variable immunodeficiency (CVID) patients seen in the United States (Mount Sinai …

Non-infectious complications of common variable immunodeficiency: updated clinical spectrum, sequelae, and insights to pathogenesis

H Ho, C Cunningham-Rundles - Frontiers in immunology, 2020‏ - frontiersin.org
Non-infectious complications in common variable immunodeficiency (CVID) have emerged
as a major clinical challenge. Detailed clinical spectrum, organ-specific pathologies and …

T follicular helper cells in autoimmune disorders

N Gensous, M Charrier, D Duluc… - Frontiers in …, 2018‏ - frontiersin.org
T follicular helper (Tfh) cells are a distinct subset of CD4+ T lymphocytes, specialized in B
cell help and in regulation of antibody responses. They are required for the generation of …

[PDF][PDF] Common variable immunodeficiency: epidemiology, pathogenesis, clinical manifestations, diagnosis, classification and management

I Karaj - J Investig Allergol Clin Immunol, 2020‏ - scholar.archive.org
Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by
hypogammaglobulinemia and increased susceptibility to recurrent bacterial infections. It is …

Human neutrophils drive skin autoinflammation by releasing interleukin (IL)-26

A Baldo, J Di Domizio, A Yatim… - Journal of Experimental …, 2024‏ - rupress.org
Human neutrophils drive skin autoinflammation by releasing interleukin (IL)-26 | Journal of
Experimental Medicine | Rockefeller University Press Skip to Main Content Advertisement …

Emerging insights into human health and NK cell biology from the study of NK cell deficiencies

EM Mace, JS Orange - Immunological reviews, 2019‏ - Wiley Online Library
Human NK cells are innate immune effectors that play a critical roles in the control of viral
infection and malignancy. The importance of their homeostasis and function can be …

The TH1 phenotype of follicular helper T cells indicates an IFN-γ–associated immune dysregulation in patients with CD21low common variable immunodeficiency

S Unger, M Seidl, P van Schouwenburg… - Journal of allergy and …, 2018‏ - Elsevier
Background A subgroup of patients with common variable immunodeficiency (CVID)
experience immune dysregulation manifesting as autoimmunity, lymphoproliferation, and …

Gastrointestinal disorders associated with common variable immune deficiency (CVID) and chronic granulomatous disease (CGD)

M Uzzan, HM Ko, S Mehandru… - Current …, 2016‏ - Springer
Common variable immune deficiency (CVID) and chronic granulomatous disease (CGD) are
two of the well-characterized primary immune deficiencies with distinct pathologic defects …

Emerging concepts and future challenges in innate lymphoid cell biology

ED Tait Wojno, D Artis - Journal of Experimental Medicine, 2016‏ - rupress.org
Innate lymphoid cells (ILCs) are innate immune cells that are ubiquitously distributed in
lymphoid and nonlymphoid tissues and enriched at mucosal and barrier surfaces. Three …