Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Fluorescent probes for the detection of disease-associated biomarkers

WT Dou, HH Han, AC Sedgwick, GB Zhu, Y Zang… - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …

Chemiluminescence for bioimaging and therapeutics: recent advances and challenges

M Yang, J Huang, J Fan, J Du, K Pu… - Chemical Society Reviews, 2020 - pubs.rsc.org
Chemiluminescence, the generation of light through chemiexcitation as a result of chemical
reactions, has emerged as a novel tool for bioimaging and therapy in vivo. Due to the …

Preparation of AIEgen-based near-infrared afterglow luminescence nanoprobes for tumor imaging and image-guided tumor resection

C Chen, X Zhang, Z Gao, G Feng, D Ding - Nature Protocols, 2024 - nature.com
Fluorescence imaging represents a vital tool in modern biology, oncology and biomedical
applications. Afterglow luminescence (AGL), which circumvents the light scattering and …

Activatable molecular probes for second near‐infrared fluorescence, chemiluminescence, and photoacoustic imaging

J Huang, K Pu - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Optical imaging plays a crucial role in biomedicine. However, due to strong light scattering
and autofluorescence in biological tissue between 650–900 nm, conventional optical …

Development of organic semiconducting materials for deep-tissue optical imaging, phototherapy and photoactivation

J Li, K Pu - Chemical Society Reviews, 2019 - pubs.rsc.org
Biophotonics as a highly interdisciplinary frontier often requires the assistance of optical
agents to control the light pathways in cells, tissues and living organisms for specific …

Near‐infrared photodynamic chemiluminescent probes for cancer therapy and metastasis detection

J Huang, C Zhang, X Wang, X Wei… - Angewandte Chemie, 2023 - Wiley Online Library
There is growing interest in the development of chemiluminescence (CL) probes for
phototheranostics because of their minimized tissue autofluorescence. However, due to a …

Amplification of activated near-infrared afterglow luminescence by introducing twisted molecular geometry for understanding neutrophil-involved diseases

C Chen, H Gao, H Ou, RTK Kwok, Y Tang… - Journal of the …, 2022 - ACS Publications
Understanding the mechanism and progression of neutrophil-involved diseases (eg, acute
inflammation) is of great importance. However, current available analytical methods neither …

Near-infrared afterglow luminescent aggregation-induced emission dots with ultrahigh tumor-to-liver signal ratio for promoted image-guided cancer surgery

X Ni, X Zhang, X Duan, HL Zheng, XS Xue, D Ding - Nano letters, 2018 - ACS Publications
Afterglow imaging through the collection of persistent luminescence after the stop** of
light excitation holds enormous promise for advanced biomedical uses. However, efficient …