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Evaluation and management of Non-variceal upper gastrointestinal bleeding
Non-variceal upper gastrointestinal bleeding continues to be an important cause of
morbidity and mortality. The most common causes include peptic ulcer disease, Mallory …
morbidity and mortality. The most common causes include peptic ulcer disease, Mallory …
Risk of major gastrointestinal bleeding with new vs conventional oral anticoagulants: a systematic review and meta-analysis
Background & Aims There is controversy over whether use of non-vitamin K antagonist oral
anticoagulants (NOACs) associates with increased risk of major gastrointestinal bleeding …
anticoagulants (NOACs) associates with increased risk of major gastrointestinal bleeding …
Rivaroxaban is associated with higher rates of gastrointestinal bleeding than other direct oral anticoagulants: A nationwide propensity score–weighted study
Background: Gastrointestinal bleeding (GIB) rates for direct oral anticoagulants (DOACs)
and warfarin have been extensively compared. However, population-based studies …
and warfarin have been extensively compared. However, population-based studies …
Mortality rate and risk factors for gastrointestinal bleeding in elderly patients
Background Gastrointestinal bleeding (GIB) is burdened by high mortality rate that increases
with aging. Elderly patients may be exposed to multiple risk factors for GIB. We aimed at …
with aging. Elderly patients may be exposed to multiple risk factors for GIB. We aimed at …
Risk of gastrointestinal bleeding during anticoagulant treatment
Introduction: Gastrointestinal bleeding (GIB) is a major problem in patients on oral
anticoagulation therapy. This issue has become even more pressing since the introduction …
anticoagulation therapy. This issue has become even more pressing since the introduction …
Gastrointestinal bleeding risk with direct oral anticoagulants
Purpose Although direct oral anticoagulants (DOACs) are associated with an overall
favourable safety profile, the risk of gastrointestinal bleeding with DOACs compared with …
favourable safety profile, the risk of gastrointestinal bleeding with DOACs compared with …
A systematic review of network meta-analyses among patients with nonvalvular atrial fibrillation: a comparison of efficacy and safety following treatment with direct oral …
Abstract Background Direct oral anticoagulants (DOACs) are indicated for the prevention of
stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation. While no …
stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation. While no …
[HTML][HTML] Design and fabrication of r-hirudin loaded dissolving microneedle patch for minimally invasive and long-term treatment of thromboembolic disease
M Wu, T **a, Y Li, T Wang, S Yang, J Yu… - Asian journal of …, 2022 - Elsevier
Cardiovascular disease is the leading cause of global mortality, with anticoagulant therapy
being the main prevention and treatment strategy. Recombinant hirudin (r-hirudin) is a direct …
being the main prevention and treatment strategy. Recombinant hirudin (r-hirudin) is a direct …
Do proton pump inhibitors reduce upper gastrointestinal bleeding in older patients with atrial fibrillation treated with oral anticoagulants? A nationwide cohort study in …
Abstract Background Proton pump inhibitors (PPIs) are largely used in older adults and data
are needed in off-label indications, such as the prevention of upper gastrointestinal bleeding …
are needed in off-label indications, such as the prevention of upper gastrointestinal bleeding …
Differences in gastrointestinal safety profiles among novel oral anticoagulants: Evidence from a network meta-analysis
WQ Guo, XH Chen, XY Tian, L Li - Clinical Epidemiology, 2019 - Taylor & Francis
Background There is no consensus at present regarding the differences in the risk of GI
bleeding across various NOAC regimens. Therefore, we performed a network meta-analysis …
bleeding across various NOAC regimens. Therefore, we performed a network meta-analysis …