[HTML][HTML] Integration strategies of multi-omics data for machine learning analysis
Increased availability of high-throughput technologies has generated an ever-growing
number of omics data that seek to portray many different but complementary biological …
number of omics data that seek to portray many different but complementary biological …
Environmental triggers in IBD: a review of progress and evidence
AN Ananthakrishnan, CN Bernstein… - Nature reviews …, 2018 - nature.com
A number of environmental factors have been associated with the development of IBD.
Alteration of the gut microbiota, or dysbiosis, is closely linked to initiation or progression of …
Alteration of the gut microbiota, or dysbiosis, is closely linked to initiation or progression of …
DIABLO: an integrative approach for identifying key molecular drivers from multi-omics assays
Motivation In the continuously expanding omics era, novel computational and statistical
strategies are needed for data integration and identification of biomarkers and molecular …
strategies are needed for data integration and identification of biomarkers and molecular …
[HTML][HTML] Multi-omics approaches in cancer research with applications in tumor subty**, prognosis, and diagnosis
While cost-effective high-throughput technologies provide an increasing amount of data, the
analyses of single layers of data seldom provide causal relations. Multi-omics data …
analyses of single layers of data seldom provide causal relations. Multi-omics data …
The IBD interactome: an integrated view of aetiology, pathogenesis and therapy
Crohn's disease and ulcerative colitis are prototypical complex diseases characterized by
chronic and heterogeneous manifestations, induced by interacting environmental, genomic …
chronic and heterogeneous manifestations, induced by interacting environmental, genomic …
A selective review of multi-level omics data integration using variable selection
High-throughput technologies have been used to generate a large amount of omics data. In
the past, single-level analysis has been extensively conducted where the omics …
the past, single-level analysis has been extensively conducted where the omics …
Approaches to integrating metabolomics and multi-omics data: a primer
T Jendoubi - Metabolites, 2021 - mdpi.com
Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …
and how these are influenced by external or internal perturbations. It lies at the heart of …
Missing data in multi-omics integration: Recent advances through artificial intelligence
JE Flores, DM Claborne, ZD Weller… - Frontiers in Artificial …, 2023 - frontiersin.org
Biological systems function through complex interactions between various 'omics
(biomolecules), and a more complete understanding of these systems is only possible …
(biomolecules), and a more complete understanding of these systems is only possible …
Host and microbiome multi-omics integration: applications and methodologies
The study of the microbial community—the microbiome—associated with a human host is a
maturing research field. It is increasingly clear that the composition of the human's …
maturing research field. It is increasingly clear that the composition of the human's …
[HTML][HTML] Statistical methods for mediation analysis in the era of high-throughput genomics: current successes and future challenges
Mediation analysis investigates the intermediate mechanism through which an exposure
exerts its influence on the outcome of interest. Mediation analysis is becoming increasingly …
exerts its influence on the outcome of interest. Mediation analysis is becoming increasingly …