Neuronal injuries in cerebral infarction and ischemic stroke: From mechanisms to treatment

Y Zhao, X Zhang, X Chen… - … journal of molecular …, 2022 - spandidos-publications.com
Stroke is the leading cause of disabilities and cognitive deficits, accounting for 5.2% of all
mortalities worldwide. Transient or permanent occlusion of cerebral vessels leads to …

Neuronal regulation of immunity: why, how and where?

M Schiller, TL Ben-Shaanan, A Rolls - Nature Reviews Immunology, 2021 - nature.com
Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …

Extracellular vesicles improve post-stroke neuroregeneration and prevent postischemic immunosuppression

TR Doeppner, J Herz, A Görgens… - Stem cells …, 2015 - academic.oup.com
Although the initial concepts of stem cell therapy aimed at replacing lost tissue, more recent
evidence has suggested that stem and progenitor cells alike promote postischemic …

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

J Montaner, L Ramiro, A Simats, S Tiedt… - Nature Reviews …, 2020 - nature.com
Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

[HTML][HTML] Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production

A Houlden, M Goldrick, D Brough, ES Vizi… - Brain, behavior, and …, 2016 - Elsevier
Intestinal microbiota are critical for health with changes associated with diverse human
diseases. Research suggests that altered intestinal microbiota can profoundly affect brain …

Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: review and recommendations of the COSBID research group

JP Dreier, M Fabricius, C Ayata… - Journal of Cerebral …, 2017 - journals.sagepub.com
Spreading depolarizations (SD) are waves of abrupt, near-complete breakdown of neuronal
transmembrane ion gradients, are the largest possible pathophysiologic disruption of viable …

[HTML][HTML] Autonomic nervous system and immune system interactions

MJ Kenney, CK Ganta - Comprehensive physiology, 2014 - ncbi.nlm.nih.gov
The present review assesses the current state of literature defining integrative autonomic-
immune physiological processing, focusing on studies that have employed …

Stroke-associated pneumonia: major advances and obstacles

Y Hannawi, B Hannawi, CPV Rao, JI Suarez… - Cerebrovascular …, 2013 - karger.com
Background: Stroke-associated pneumonia (SAP) has been implicated in the morbidity,
mortality and increased medical cost after acute ischemic stroke. The annual cost of SAP …

Role of blood-based biomarkers in ischemic stroke prognosis: a systematic review

FA Montellano, K Ungethüm, L Ramiro, A Nacu… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Outcome prognostication in ischemic stroke patients remains
challenging due to limited predictive properties of existing models. Blood-based biomarkers …

Neutrophil-to-lymphocyte ratio in acute cerebral hemorrhage: a system review

S Lattanzi, F Brigo, E Trinka, C Cagnetti… - Translational stroke …, 2019 - Springer
Spontaneous intracerebral hemorrhage (ICH) accounts for approximately 10 to 30% of all
acute cerebrovascular events, and it is the type of stroke associated with the highest rates of …