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Computational modeling of realistic cell membranes
Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …
Physical properties of blood and their relationship to clinical conditions
It has been long known that blood health heavily influences optimal physiological function.
Abnormalities affecting the physical properties of blood have been implicated in the …
Abnormalities affecting the physical properties of blood have been implicated in the …
Artificial cells for in vivo biomedical applications through red blood cell biomimicry
J Waeterschoot, W Gosselé, Š Lemež… - Nature …, 2024 - nature.com
Recent research in artificial cell production holds promise for the development of delivery
agents with therapeutic effects akin to real cells. To succeed in these applications, these …
agents with therapeutic effects akin to real cells. To succeed in these applications, these …
Backmap** triangulated surfaces to coarse-grained membrane models
Many biological processes involve large-scale changes in membrane shape. Computer
simulations of these processes are challenging since they occur across a wide range of …
simulations of these processes are challenging since they occur across a wide range of …
Metabolic influences modulating erythrocyte deformability and eryptosis
JF Brun, E Varlet-Marie, J Myzia… - Metabolites, 2021 - mdpi.com
Many factors in the surrounding environment have been reported to influence erythrocyte
deformability. It is likely that some influences represent reversible changes in erythrocyte …
deformability. It is likely that some influences represent reversible changes in erythrocyte …
Advances in microfluidics for single red blood cell analysis
GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …
Venous thromboembolism: review of Clinical challenges, Biology, Assessment, Treatment, and modeling
Venous thromboembolism (VTE) is a massive clinical challenge, annually affecting millions
of patients globally. VTE is a particularly consequential pathology, as incidence is correlated …
of patients globally. VTE is a particularly consequential pathology, as incidence is correlated …
[HTML][HTML] Red blood cells tracking and cell-free layer formation in a microchannel with hyperbolic contraction: A CFD model validation
Abstract Background and Objective In recent years, progress in microfabrication
technologies has attracted the attention of researchers across disciplines. Microfluidic …
technologies has attracted the attention of researchers across disciplines. Microfluidic …
Biophysical and biomolecular interactions of malaria-infected erythrocytes in engineered human capillaries
Microcirculatory obstruction is a hallmark of severe malaria, but mechanisms of parasite
sequestration are only partially understood. Here, we developed a robust three-dimensional …
sequestration are only partially understood. Here, we developed a robust three-dimensional …
Red blood cell shape transitions and dynamics in time-dependent capillary flows
SM Recktenwald, K Graessel, FM Maurer, T John… - Biophysical …, 2022 - cell.com
The dynamics of single red blood cells (RBCs) determine microvascular blood flow by
adapting their shape to the flow conditions in the narrow vessels. In this study, we explore …
adapting their shape to the flow conditions in the narrow vessels. In this study, we explore …