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Mitochondrial dysfunction and chronic inflammation in polycystic ovary syndrome
Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …
Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …
disorder that manifests in genetically susceptible women following a range of negative …
Identification of key genes associated with polycystic ovary syndrome (PCOS) and ovarian cancer using an integrated bioinformatics analysis
J Zou, Y Li, N Liao, J Liu, Q Zhang, M Luo… - Journal of ovarian …, 2022 - Springer
Background Accumulating evidence suggests a strong association between polycystic ovary
syndrome (PCOS) and ovarian cancer (OC), but the potential molecular mechanism remains …
syndrome (PCOS) and ovarian cancer (OC), but the potential molecular mechanism remains …
[HTML][HTML] The epigenetic correlation among ovarian cancer, endometriosis and PCOS: A review
Ovarian cancer is a frequent malignancy that affects a large percentage of women.
Endometriosis is a chronic condition, where there is a production of benign lesions were …
Endometriosis is a chronic condition, where there is a production of benign lesions were …
Integrated multi-omics analysis reveals the molecular interplay between circadian clocks and cancer pathogenesis
Circadian rhythms (CRs) are fundamental biological processes that significantly impact
human well-being. Disruption of these rhythms can trigger insufficient neurocognitive …
human well-being. Disruption of these rhythms can trigger insufficient neurocognitive …
The pharmacoepigenetic paradigm in cancer treatment
Epigenetic modifications, characterized by changes in gene expression without altering the
DNA sequence, play a crucial role in the development and progression of cancer by …
DNA sequence, play a crucial role in the development and progression of cancer by …
Unraveling druggable cancer-driving proteins and targeted drugs using artificial intelligence and multi-omics analyses
The druggable proteome refers to proteins that can bind to small molecules with appropriate
chemical affinity, inducing a favorable clinical response. Predicting druggable proteins …
chemical affinity, inducing a favorable clinical response. Predicting druggable proteins …
Pathophysiological effects of contemporary lifestyle on evolutionary-conserved survival mechanisms in polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is increasingly being characterized as an evolutionary
mismatch disorder that presents with a complex mixture of metabolic and endocrine …
mismatch disorder that presents with a complex mixture of metabolic and endocrine …
Effect of Triclisia subcordata Oliv.(Menispermaceae) leaves on hormonal imbalance and genes expression in the ovaries of letrozole-induced polycystic rats via in vivo …
The hormonal imbalance, insulin sensitivity, and ovarian function are among the biological
processes linked to polycystic ovarian syndrome (PCOS). Hence, in PCOS ovaries, the …
processes linked to polycystic ovarian syndrome (PCOS). Hence, in PCOS ovaries, the …
Mitochondrial dysfunction in polycystic ovary syndrome
J Finsterer - Reproductive Sciences, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a multi-causal condition. Among the genetic causes,
variations in the mitochondrial DNA (mtDNA) are increasingly recognised as causative …
variations in the mitochondrial DNA (mtDNA) are increasingly recognised as causative …