Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

The intracellular calcium ions (Ca 2+) act as second messenger to regulate gene
transcription, cell proliferation, migration and death. Accumulating evidences have …

The old Greek aphorism 'Panta Rhei'('everything flows') is true for all living things in general.
As a dynamic process, calcium signaling plays fundamental roles in cellular activities under …

Since the discovery of the participation of various ion channels in the regulation of cell
proliferation and programmed cell death two decades ago, the field exploring ion channel …

Cellular life strongly depends on the membrane ability to precisely control exchange of
solutes between the internal and external (environmental) compartments. This barrier …

Ion channels have been shown to be involved in oncogenesis and efforts are being poured
in to target the ion channels. There are many clinically approved drugs with ion channels as …

The proteasome system is a large and complex molecular machinery responsible for the
degradation of misfolded, damaged, and redundant cellular proteins. When proteasome …

T-type calcium channels are involved in a multitude of cellular processes, both physiological
and pathological, including cancer. T-type channels are also often aberrantly expressed in …

T-type calcium channels are expressed in many diverse tissues, including neuronal,
cardiovascular, and endocrine. T-type calcium channels are known to play roles in the …

Complex multicellular organisms are composed of distinct tissues involving specialized cells
that can perform specific functions, making such life forms possible. Species are defined by …