A growing body of evidence highlights that several insults during pregnancy impact the
vascular function and immune response of the male and female offspring. Overactivation of …

Macrophages are integral components of the innate immune system that colonize organs
early in development and persist into adulthood through self-renewal. Their fate, whether …

In the era of renewed space exploration, comprehending the effects of the space
environment on human health, particularly for deep space missions, is crucial. While …

Epidemiological studies suggest that fetal growth restriction (FGR) caused by gestational
cholestasis is associated with elevated serum cholic acid (CA). Here, we explore the …

Aim Fetal growth restriction (FGR) can lead to short‐term and long‐term impairments in the
fetus. The placenta functions as an exchanger for substance transport, playing a critical role …

Prenatal glucocorticoid overexposure alters the developmental program of fetal reproductive
organs and results in numerous changes that can lead to various disorders later in life …

Prednisone, a synthetic glucocorticoid, is commonly used to treat autoimmune diseases in
pregnant women. However, some studies suggest that the use of prednisone during …

Preeclampsia (PE) is a complex human‐specific complication frequently associated with
placental pathology. The local renin‐angiotensin system (RAS) in the human placenta …

宫内生长受限(intrauterine growth restriction, IUGR) 的发生可能与母体营养不良,
胎盘功能异常, 免疫异常, 遗传相关问题以及其他疾病有关, 但其机制尚不明确. 因此, IUGR …

Fetal-originated diseases refer to birth defects of offspring and multiple chronic diseases in
adulthood caused by abnormal embryonic development. However, due to the vulnerability of …