Most human cells utilize glucose as the primary substrate, cellular uptake requiring insulin.
Insulin signaling is therefore critical for these tissues. However, decrease in insulin …

Aging and diabetes mellitus are 2 well-known risk factors for cardiovascular disease (CVD).
During the past 50 years, there has been an dramatic increase in life expectancy with a …

Primary aging is the progressive and inevitable process of bodily deterioration during
adulthood. In skeletal muscle, primary aging causes defective mitochondrial energetics and …

Inactive adults experience a 3% to 8% loss of muscle mass per decade, accompanied by
resting metabolic rate reduction and fat accumulation. Ten weeks of resistance training may …

The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of ischemic stroke among survivors of ischemic stroke …

Methods for assessment, eg., anthropometric indicators and imaging techniques, of several
phenotypes of human obesity, with special reference to abdominal fat content, have been …

Objective Obesity (as defined by body mass index) has not been associated consistently
with higher mortality in older adults. However, total body mass includes fat and muscle …

Nearly a quarter of older adults in the US have type 2 diabetes, and this population is
continuing to increase with the aging of the population. Older adults are at high risk for the …

Abstract In the United Kingdom (UK), it is projected that by 2035 people aged> 65 years will
make up 23% of the population, with those aged> 85 years accounting for 5% of the total …

Cumulative mtDNA damage occurs in aging animals, and mtDNA mutations are reported to
accelerate aging in mice. We determined whether aging results in increased DNA oxidative …