Humanity is suffering from cancer which has become a root cause of untimely deaths of
individuals around the globe in the recent past. Nanotheranostics integrates therapeutics …

Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is a
versatile MRI method that provides contrast based on the level of molecular and metabolic …

Image-guided nanotheranostics have the potential to represent a new paradigm in the
treatment of cancer. Recent developments in modern imaging and nanoparticle design offer …

Purpose Chemical exchange saturation transfer (CEST) MRI is promising for detecting dilute
metabolites and microenvironment properties, which has been increasingly adopted in …

Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
emerged as a novel means for sensitive detection of dilute labile protons and chemical …

Purpose CEST provides a MR contrast mechanism sensitizing to the exchange between
dilute labile and bulk water protons. However, the CEST effect depends on the RF saturation …

Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several
indications has yielded improved prognosis for cases where traditional therapy has shown …

Solid tumors such as prostate cancer (PCa) commonly develop an acidic microenvironment
with pH 6.5–7.2, owing to heterogeneous perfusion, high metabolic activity, and rapid cell …

Purpose Chemical exchange saturation transfer (CEST) imaging measurement depends not
only on the labile proton concentration and pH‐dependent exchange rate but also on …

Altered metabolism is considered a core hallmark of cancer. By monitoring in vivo
metabolites changes or characterizing the tumor microenvironment, non-invasive imaging …