The R language: an engine for bioinformatics and data science
The R programming language is approaching its 30th birthday, and in the last three decades
it has achieved a prominent role in statistics, bioinformatics, and data science in general. It …
it has achieved a prominent role in statistics, bioinformatics, and data science in general. It …
Bioinformatics and machine learning methodologies to identify the effects of central nervous system disorders on glioblastoma progression
Glioblastoma (GBM) is a common malignant brain tumor which often presents as a
comorbidity with central nervous system (CNS) disorders. Both CNS disorders and GBM …
comorbidity with central nervous system (CNS) disorders. Both CNS disorders and GBM …
An SHR–SCR module specifies legume cortical cell fate to enable nodulation
W Dong, Y Zhu, H Chang, C Wang, J Yang, J Shi… - Nature, 2021 - nature.com
Legumes, unlike other plants, have the ability to establish symbiosis with nitrogen-fixing
rhizobia. It has been theorized that a unique property of legume root cortical cells enabled …
rhizobia. It has been theorized that a unique property of legume root cortical cells enabled …
Polystyrene nanoplastic induces oxidative stress, immune defense, and glycometabolism change in Daphnia pulex: Application of transcriptome profiling in risk …
Aquatic environments are generally contaminated with nanoplastic material. As a result,
molecular mechanisms for sensitive species like Daphnia are needed, given that …
molecular mechanisms for sensitive species like Daphnia are needed, given that …
[HTML][HTML] Immune signature-based subtypes of cervical squamous cell carcinoma tightly associated with human papillomavirus type 16 expression, molecular features …
X Lu, L Jiang, L Zhang, Y Zhu, W Hu, J Wang, X Ruan… - Neoplasia, 2019 - Elsevier
Substantial heterogeneity exists within cervical cancer that is generally infected by human
papillomavirus (HPV). However, the most common histological subtype of cervical cancer …
papillomavirus (HPV). However, the most common histological subtype of cervical cancer …
Expansion of GGC repeat in GIPC1 is associated with oculopharyngodistal myopathy
Oculopharyngodistal myopathy (OPDM) is an adult-onset inherited neuromuscular disorder
characterized by progressive ptosis, external ophthalmoplegia, and weakness of the …
characterized by progressive ptosis, external ophthalmoplegia, and weakness of the …
Dietary polystyrene nanoplastics exposure alters hepatic glycolipid metabolism, triggering inflammatory responses and apoptosis in Monopterus albus
Microplastics and nanoplastics (MPs and NPs) are abundant, persistent, and widespread
environmental pollutants that are of increasing concern as they pose a serious threat to …
environmental pollutants that are of increasing concern as they pose a serious threat to …
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis
Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic
itch diseases are thought to be driven by both the nervous and immune systems, but the …
itch diseases are thought to be driven by both the nervous and immune systems, but the …
Single‐base methylome analysis reveals dynamic epigenomic differences associated with water deficit in apple
J Xu, S Zhou, X Gong, Y Song… - Plant biotechnology …, 2018 - Wiley Online Library
Cytosine methylation is an essential feature of epigenetic regulation and is involved in
various biological processes. Although cytosine methylation has been analysed at the …
various biological processes. Although cytosine methylation has been analysed at the …
bayNorm: Bayesian gene expression recovery, imputation and normalization for single-cell RNA-sequencing data
Motivation Normalization of single-cell RNA-sequencing (scRNA-seq) data is a prerequisite
to their interpretation. The marked technical variability, high amounts of missing …
to their interpretation. The marked technical variability, high amounts of missing …