Biomarkers of checkpoint inhibitor induced immune-related adverse events—a comprehensive review
Immune checkpoint inhibitors (ICIs) have substantially improved the prognosis of patients
with different types of cancer. Through blockade of cytotoxic T-lymphocyte antigen 4 (CTLA …
with different types of cancer. Through blockade of cytotoxic T-lymphocyte antigen 4 (CTLA …
Classical examples of the concept of the ASIA syndrome
V Borba, A Malkova, N Basantsova, G Halpert… - Biomolecules, 2020 - mdpi.com
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) was first introduced in
2011 by Shoenfeld et al. and encompasses a cluster of related immune mediated diseases …
2011 by Shoenfeld et al. and encompasses a cluster of related immune mediated diseases …
Immune checkpoint inhibitor-associated pneumonitis in non-small cell lung cancer: current understanding in characteristics, diagnosis, and management
Q Zhang, L Tang, Y Zhou, W He, W Li - Frontiers in immunology, 2021 - frontiersin.org
Immunotherapy that includes programmed cell death-1 (PD-1), programmed cell death-
ligand 1 (PD-L1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibitors has …
ligand 1 (PD-L1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibitors has …
Predictive biomarkers for checkpoint inhibitor immune-related adverse events
I Les, M Martinez, I Perez-Francisco, M Cabero… - Cancers, 2023 - mdpi.com
Simple Summary Immune-checkpoint inhibitors (ICIs) are increasingly used in the treatment
of cancer, but they cause immune-related adverse events (irAEs) in around 40% of patients …
of cancer, but they cause immune-related adverse events (irAEs) in around 40% of patients …
Checkpoint inhibitor pneumonitis induced by anti-PD-1/PD-L1 therapy in non-small-cell lung cancer: occurrence and mechanism
J Yin, Y Wu, X Yang, L Gan, J Xue - Frontiers in Immunology, 2022 - frontiersin.org
Immune checkpointty inhibitors (ICIs), particularly those targeting programmed death 1 (PD-
1) and anti-programmed death ligand 1 (PD-L1), enhance the antitumor effect by restoring …
1) and anti-programmed death ligand 1 (PD-L1), enhance the antitumor effect by restoring …
Multi-omics analysis uncovers tumor ecosystem dynamics during neoadjuvant toripalimab plus nab-paclitaxel and S-1 for esophageal squamous cell carcinoma: a …
G Zhang, J Yuan, C Pan, Q Xu, X Cui, J Zhang, M Liu… - …, 2023 - thelancet.com
Background Immune checkpoint inhibitors combined with chemotherapy as a neoadjuvant
therapy have been applied to the treatment of esophageal squamous cell carcinoma …
therapy have been applied to the treatment of esophageal squamous cell carcinoma …
[HTML][HTML] Biomarkers, clinical features, and rechallenge for immune checkpoint inhibitor renal immune-related adverse events
B Isik, MP Alexander, S Manohar, L Vaughan… - Kidney International …, 2021 - Elsevier
Introduction Immune checkpoint inhibitors (ICIs) are effective in treating several cancers;
however, acute kidney injury (AKI) can occur as part as an immune-related adverse event …
however, acute kidney injury (AKI) can occur as part as an immune-related adverse event …
[HTML][HTML] The mechanism and risk factors for immune checkpoint inhibitor pneumonitis in non-small cell lung cancer patients
X Zhai, J Zhang, Y Tian, J Li, W **g… - Cancer Biology & …, 2020 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are new and promising therapeutic agents for non-small
cell lung cancer (NSCLC). However, along with demonstrating remarkable efficacy, ICIs can …
cell lung cancer (NSCLC). However, along with demonstrating remarkable efficacy, ICIs can …
[HTML][HTML] Gut microbiota changes and its potential relations with thyroid carcinoma
X Yu, W Jiang, RO Kosik, Y Song, Q Luo, T Qiao… - Journal of advanced …, 2022 - Elsevier
Introduction Emerging evidence suggests that the essence of life is the ecological balance of
the neural, endocrine, metabolic, microbial, and immune systems. Gut microbiota have been …
the neural, endocrine, metabolic, microbial, and immune systems. Gut microbiota have been …
[HTML][HTML] Lower baseline autoantibody levels are associated with immune-related adverse events from immune checkpoint inhibition
Methods This study used data from an oncologic clinical trial of adaptive dosing combination
ICI therapy in patients with advanced melanoma. Plasma was collected at baseline and 6 …
ICI therapy in patients with advanced melanoma. Plasma was collected at baseline and 6 …