Protein secondary structure prediction continues to rise

B Rost - Journal of structural biology, 2001 - Elsevier
Methods predicting protein secondary structure improved substantially in the 1990s through
the use of evolutionary information taken from the divergence of proteins in the same …

Use of machine learning approaches for novel drug discovery

AN Lima, EA Philot, GHG Trossini… - Expert opinion on …, 2016 - Taylor & Francis
abstract Introduction: The use of computational tools in the early stages of drug development
has increased in recent decades. Machine learning (ML) approaches have been of special …

[BOOK][B] Bioinformatics: the machine learning approach

P Baldi, S Brunak - 2001 - books.google.com
A guide to machine learning approaches and their application to the analysis of biological
data. An unprecedented wealth of data is being generated by genome sequencing projects …

[BOOK][B] Kernel methods in computational biology

B Schölkopf, K Tsuda, JP Vert - 2004 - books.google.com
A detailed overview of current research in kernel methods and their application to
computational biology. Modern machine learning techniques are proving to be extremely …

Improving the prediction of protein secondary structure in three and eight classes using recurrent neural networks and profiles

G Pollastri, D Przybylski, B Rost… - … : Structure, Function, and …, 2002 - Wiley Online Library
Secondary structure predictions are increasingly becoming the workhorse for several
methods aiming at predicting protein structure and function. Here we use ensembles of …

A generic method for assignment of reliability scores applied to solvent accessibility predictions

B Petersen, TN Petersen, P Andersen, M Nielsen… - BMC structural …, 2009 - Springer
Background Estimation of the reliability of specific real value predictions is nontrivial and the
efficacy of this is often questionable. It is important to know if you can trust a given prediction …

[BOOK][B] Deep learning in science

P Baldi - 2021 - books.google.com
This is the first rigorous, self-contained treatment of the theory of deep learning. Starting with
the foundations of the theory and building it up, this is essential reading for any scientists …

A Deep Learning Network Approach to ab initio Protein Secondary Structure Prediction

M Spencer, J Eickholt, J Cheng - IEEE/ACM transactions on …, 2014 - ieeexplore.ieee.org
Ab initio protein secondary structure (SS) predictions are utilized to generate tertiary
structure predictions, which are increasingly demanded due to the rapid discovery of …

Porter: a new, accurate server for protein secondary structure prediction

G Pollastri, A McLysaght - Bioinformatics, 2005 - academic.oup.com
Porter is a new system for protein secondary structure prediction in three classes. Porter
relies on bidirectional recurrent neural networks with shortcut connections, accurate coding …

CPHmodels-3.0—remote homology modeling using structure-guided sequence profiles

M Nielsen, C Lundegaard, O Lund… - Nucleic acids …, 2010 - academic.oup.com
Abstract CPHmodels-3.0 is a web server predicting protein 3D structure by use of single
template homology modeling. The server employs a hybrid of the scoring functions of …