Developmental biology of the meninges

K Dasgupta, J Jeong - Genesis, 2019 - Wiley Online Library
The meninges are membranous layers surrounding the central nervous system. In the head,
the meninges lie between the brain and the skull, and interact closely with both during …

[HTML][HTML] Neurovascular crosstalk coordinates the central nervous system development

B Peguera, M Segarra, A Acker-Palmer - Current opinion in neurobiology, 2021 - Elsevier
Purpose of the review: The synchronic development of vascular and nervous systems is
orchestrated by common molecules that regulate the communication between both systems …

PDGFRβ cells rapidly relay inflammatory signal from the circulatory system to neurons via chemokine CCL2

L Duan, XD Zhang, WY Miao, YJ Sun, G **ong, Q Wu… - Neuron, 2018 - cell.com
Acute infection, if not kept in check, can lead to systemic inflammatory responses in the
brain. Here, we show that within 2 hr of systemic inflammation, PDGFRβ mural cells of blood …

Stroke and neurogenesis: bridging clinical observations to new mechanistic insights from animal models

JP Passarelli, SM Nimjee, KL Townsend - Translational stroke research, 2024 - Springer
Stroke was the 2nd leading cause of death and a major cause of morbidity. Unfortunately,
there are limited means to promote neurological recovery post-stroke, but research has …

New neurons in adult brain: distribution, molecular mechanisms and therapies

A Pino, G Fumagalli, F Bifari, I Decimo - Biochemical pharmacology, 2017 - Elsevier
Abstract “Are new neurons added in the adult mammalian brain?”“Do neural stem cells
activate following CNS diseases?”“How can we modulate their activation to promote …

Microglial displacement of GABAergic synapses is a protective event during complex febrile seizures

Y Wan, B Feng, Y You, J Yu, C Xu, H Dai, BD Trapp… - Cell Reports, 2020 - cell.com
Complex febrile seizures (FSs) lead to a high risk of intractable temporal lobe epilepsy
during adulthood, yet the pathological process of complex FSs is largely unknown. Here, we …

Blood vessels as regulators of neural stem cell properties

A Karakatsani, B Shah… - Frontiers in Molecular …, 2019 - frontiersin.org
In the central nervous system (CNS), a precise communication between the vascular and
neural compartments is essential for proper development and function. Recent studies …

Sex-specific eNOS activity and function in human endothelial cells

MG Cattaneo, C Vanetti, I Decimo, M Di Chio… - Scientific reports, 2017 - nature.com
Clinical and epidemiological data show that biological sex is one of the major determinants
for the development and progression of cardiovascular disease (CVD). Impaired endothelial …

Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages

Y Hu, Y Jiang, J Behnan, MM Ribeiro, C Kalantzi… - Science …, 2022 - science.org
Glioblastoma is believed to originate from nervous system cells; however, a putative origin
from vessel-associated progenitor cells has not been considered. We deeply single-cell …

[HTML][HTML] Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development

X Zhou, Y Lu, F Zhao, J Dong, W Ma, S Zhong, M Wang… - Cell Stem Cell, 2022 - cell.com
The hypothalamus comprises various nuclei and neuronal subpopulations that control
fundamental homeostasis and behaviors. However, spatiotemporal molecular …