Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Inflammation underlies a wide variety of physiological and pathological processes. Although
the pathological aspects of many types of inflammation are well appreciated, their …

Human PON1 is a HDL-associated lipolactonase capable of preventing LDL and cell
membrane oxidation and is therefore considered to be atheroprotective. PON1 contributes to …

Type 2 diabetes and cardiovascular disease represent a serious threat to the health of the
population worldwide. Although overall adiposity and particularly visceral adiposity are …

Background Levels of high-density lipoprotein (HDL) cholesterol are inversely related to
cardiovascular risk. Torcetrapib, a cholesteryl ester transfer protein (CETP) inhibitor …

High-density lipoprotein (HDL) is a complex mixture of lipoproteins that is associated with
many minor proteins and lipids that influence the function of HDL. Although HDL is a …

Objective To investigate the association between treatment induced change in high density
lipoprotein cholesterol and total death, coronary heart disease death, and coronary heart …

Objectives: This study was designed to assess the relationship of high-density-lipoprotein
cholesterol (HDL-C), HDL particle size, and apolipoprotein AI (apoA-I) with the occurrence of …

ContextHigh-density lipoprotein cholesterol (HDL-C) is a cardiovascular risk factor that is
gaining substantial interest as a therapeutic target. ObjectivesTo review the current and …

Context Low levels of high-density lipoprotein (HDL) cholesterol are inversely related to
cardiovascular risk. Whether this is a causal effect is unclear. Objective To determine …