Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo
Antibiotic resistance is projected as one of the greatest threats to human health in the future
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …
Mechanistic landscape of membrane-permeabilizing peptides
Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
Multitalented synthetic antimicrobial peptides and their antibacterial, antifungal and antiviral mechanisms
Despite the great strides in healthcare during the last century, some challenges still
remained unanswered. The development of multi-drug resistant bacteria, the alarming …
remained unanswered. The development of multi-drug resistant bacteria, the alarming …
Antimicrobial peptides as anti-infective agents in pre-post-antibiotic era?
Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …
Antimicrobial peptides and small molecules targeting the cell membrane of Staphylococcus aureus
Clinical management of Staphylococcus aureus infections presents a challenge due to the
high incidence, considerable virulence, and emergence of drug resistance mechanisms …
high incidence, considerable virulence, and emergence of drug resistance mechanisms …
Liposomes as biomembrane models: Biophysical techniques for drug-membrane interaction studies
The interaction of drugs with biological membranes is a critical factor affecting their
pharmacokinetics and pharmacodynamics, so understanding how drugs interact with …
pharmacokinetics and pharmacodynamics, so understanding how drugs interact with …
Intramembrane nanoaggregates of antimicrobial peptides play a vital role in bacterial killing
Recent developments in antimicrobial peptides (AMPs) have focused on the rational design
of short sequences with less than 20 amino acids due to their relatively low synthesis costs …
of short sequences with less than 20 amino acids due to their relatively low synthesis costs …
Membrane permeability and antimicrobial peptides: Much more than just making a hole
JC Espeche, R Varas, P Maturana, AC Cutro… - Peptide …, 2024 - Wiley Online Library
Antimicrobial peptides (AMPs) are one of the elements of innate immunity that have a crucial
role in fighting infections. These molecules are produced by all kinds of cells and can …
role in fighting infections. These molecules are produced by all kinds of cells and can …
Simultaneous nanoscale surface charge and topographical map**
Nanopipettes are playing an increasingly prominent role in nanoscience, for sizing,
sequencing, delivery, detection, and map** interfacial properties. Herein, the question of …
sequencing, delivery, detection, and map** interfacial properties. Herein, the question of …
Liposomal membrane permeability assessment by fluorescence techniques: Main permeabilizing agents, applications and challenges
Liposomes are lipid vesicles made of one or multiple lipid bilayers surrounding an internal
aqueous core. They are broadly employed as models to study membrane structure and …
aqueous core. They are broadly employed as models to study membrane structure and …