Molecular classification, treatment, and genetic biomarkers in triple-negative breast cancer: a review

B Lu, E Natarajan… - … in Cancer Research …, 2023 - journals.sagepub.com
Breast cancer is the most common malignancy and the second most common cause of
cancer-related mortality in women. Triple-negative breast cancers do not express estrogen …

Molecular targets and therapeutic strategies for triple-negative breast cancer

Y Bhat, MR Thrishna, S Banerjee - Molecular Biology Reports, 2023 - Springer
Triple-negative breast cancer (TNBC) is known for its heterogeneous complexity and is often
difficult to treat. TNBC lacks the expression of major hormonal receptors like estrogen …

[HTML][HTML] Prevalence and mortality of triple-negative breast cancer in West Africa: Biologic and sociocultural factors

GC Nwagu, S Bhattarai, M Swahn, S Ahmed… - JCO Global …, 2021 - ncbi.nlm.nih.gov
Africa is the second-largest continent by population. 1 With 54 countries across five
geographical regions (Northern, Western, Middle, Eastern, and Southern Africa), the …

[HTML][HTML] Latest Therapeutical Approaches for Triple-Negative Breast Cancer: From Preclinical to Clinical Research

M Pont, M Marqués, A Sorolla - International Journal of Molecular …, 2024 - mdpi.com
Triple-negative breast cancer (TNBC) represents roughly one-sixth of all breast cancer
patients, but accounts for 30–40% of breast cancer deaths. Due to the lack of typical …

Hsa-mir-3163 and CCNB1 may be potential biomarkers and therapeutic targets for androgen receptor positive triple-negative breast cancer

P Qiu, Q Guo, Q Yao, J Chen, J Lin - PLoS One, 2021 - journals.plos.org
Breast cancer (BC) is the most common malignancy in female, but the role of androgen
receptor (AR) in triple-negative breast cancer (TNBC) is still unclear. This study aimed to …

Luminal androgen receptor (LAR) subtype of triple-negative breast cancer: molecular, morphological, and clinical features

S Vtorushin, A Dulesova, N Krakhmal - Journal of Zhejiang University …, 2022 - Springer
According to the classification presented by Lehmann BD (2016), triple-negative breast
cancer (TNBC) is a heterogeneous group of malignant tumors with four specific subtypes …

Lipidomic and membrane mechanical signatures in triple-negative breast cancer: scope for membrane-based theranostics

R Dadhich, S Kapoor - Molecular and Cellular Biochemistry, 2022 - Springer
Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer
associated with poor prognosis, higher grade, and a high rate of metastatic occurrence …

Potential epigenetic modifications implicated in triple-to quadruple-negative breast cancer transition: a review

A Muhammad, GE Forcados, BS Katsayal, RS Bako… - …, 2022 - Taylor & Francis
Current research on triple-negative breast cancer (TNBC) has resulted in delineation into
the quadruple-negative breast cancer (QNBC) subgroup. Epigenetic modifications such as …

Are transcription factors plausible oncotargets for triple negative breast cancers?

M Marqués, MA Sorolla, I Urdanibia, E Parisi, I Hidalgo… - Cancers, 2022 - mdpi.com
Simple Summary Triple negative breast cancer is a type of breast cancer that does not have
a selective and effective therapy. It is known that this cancer possesses high abundance of …

Subcellular expression pattern and clinical significance of CBX2 and CBX7 in breast cancer subtypes

S Park, J Choi, JK Song, B Jang, YH Maeng - Medical Molecular …, 2024 - Springer
Abstract Chromobox (CBX) 2 and CBX7, members of CBX family protein, show diverse
expression patterns and contrasting roles in certain cancers. We aimed to investigate the …