Review of quetiapine and its clinical applications in schizophrenia

S Kasper, F Müller-Spahn - Expert Opinion on Pharmacotherapy, 2000 - Taylor & Francis
Preclinical studies have shown that quetiapine (Seroquel™, AstraZeneca) is an atypical
antipsychotic with many similarities to clozapine. Both placebo-controlled and comparative …

The D3 dopamine receptor in cellular and organismal function

RA Shafer, B Levant - Psychopharmacology, 1998 - Springer
The D 3 dopamine receptor is a member of the family of D 2-like dopamine receptors. Since
the cloning and identification of the D 3 receptor in 1990, considerable progress has been …

c-Fos identification of neuroanatomical sites associated with haloperidol and clozapine disruption of maternal behavior in the rat

C Zhao, M Li - Neuroscience, 2010 - Elsevier
Rat maternal behavior is a complex social behavior. Most antipsychotic drugs disrupt active
maternal responses (eg, pup retrieval, pup licking and nest building). Our previous work …

Testing the validity of c-fos expression profiling to aid the therapeutic classification of psychoactive drugs

BEH Sumner, LA Cruise, DA Slattery, DR Hill… - …, 2004 - Springer
Rationale Different stimuli, including pharmacological stimuli, induce different
neuroanatomical profiles of c-fos expression. Can these profiles be used in classifying …

Involvement of adenosine A2A receptors in the induction of c-fos expression by clozapine and haloperidol

A Pinna, J Wardas, A Cozzolino, M Morelli - Neuropsychopharmacology, 1999 - Elsevier
Acute administration of the atypical antipsychotic clozapine induced a regional pattern of c-
fos expression characterized by an increase in Fos–like-immunoreactivity (FLI) in the …

Clozapine‐, but not haloperidol‐, induced increases in ΔFosB‐like immunoreactivity are completely blocked in the striatum of mice lacking D3 dopamine receptors

GS Robertson, CJ Lee, K Sridhar… - European Journal of …, 2004 - Wiley Online Library
On the basis of anatomical and pharmacological evidence, we have proposed that D3
receptor antagonism plays a role in the mediation of clozapine‐, but not haloperidol …

Differential effects of acute and chronic treatment with typical and atypical neuroleptics on c-fos mRNA expression in rat forebrain regions using non-radioactive in situ …

J Semba, MW Sakai, T Suhara, N Akanuma - Neurochemistry international, 1999 - Elsevier
The regional difference in the expression of c-fos mRNA in rat forebrain after either acute or
chronic administration of typical (haloperidol and fluphenazine) and atypical neuroleptics …

Modification of haloperidol‐induced pattern of c‐fos expression by serotonin agonists

PO Tremblay, J Gervais… - European Journal of …, 1998 - Wiley Online Library
Acute challenge with clozapine and haloperidol produce different anatomical patterns of c‐
fos expression in the forebrain. The pharmacological profile of atypical antipsychotics …

Dopamine D3 receptor antisense administration reduces basal c‐fos and NGFI‐B mRNA levels in the rat forebrain

M Tremblay, C Rouillard, D Lévesque - Synapse, 1999 - Wiley Online Library
The physiological role of the dopamine D3 receptor is still unclear. The absence of selective
pharmacological tools that can discriminate D3 over D2 receptor subtype activity is a major …

Contrasting effects of dopamine antagonists and frequency reduction on Fos expression induced by lateral hypothalamic stimulation

GE Hunt, IS McGregor - Behavioural brain research, 2002 - Elsevier
To help further identify the reward-relevant regions activated by electrical stimulation of the
lateral hypothalamus, Fos expression was quantified in 23 brain regions in naı̈ve, awake …