Malondialdehyde as a potential oxidative stress marker for allergy-oriented diseases: an update

R Cordiano, M Di Gioacchino, R Mangifesta… - Molecules, 2023 - mdpi.com
Malondialdehyde (MDA) is a compound that is derived from the peroxidation of
polyunsaturated fatty acids. It has been used as a biomarker to measure oxidative stress in …

[HTML][HTML] Revisiting the roles of filaggrin in atopic dermatitis

V Moosbrugger-Martinz, C Leprince… - International Journal of …, 2022 - mdpi.com
The discovery in 2006 that loss-of-function mutations in the filaggrin gene (FLG) cause
ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology …

[HTML][HTML] Atopic dermatitis: clinical aspects and unmet needs

F Lobefaro, G Gualdi, S Di Nuzzo, P Amerio - Biomedicines, 2022 - mdpi.com
Atopic dermatitis is a common chronic-relapsing, inflammatory and itchy eczematous skin
disorder which occurs in both children and adults. AD pathogenesis is complex and several …

Immunopathogenesis of atopic dermatitis: Focus on interleukins as disease drivers and therapeutic targets for novel treatments

K Makowska, J Nowaczyk, L Blicharz… - International journal of …, 2023 - mdpi.com
Atopic dermatitis is a chronic, recurrent inflammatory skin disorder manifesting by
eczematous lesions and intense pruritus. Atopic dermatitis develops primarily as a result of …

[HTML][HTML] Overlap** features of psoriasis and atopic dermatitis: from genetics to immunopathogenesis to phenotypes

YC Tsai, TF Tsai - International Journal of Molecular Sciences, 2022 - mdpi.com
Psoriasis (PSO) and atopic dermatitis (AD) were once considered to be mutually exclusive
diseases, but gradually regarded as a spectrum of disease. Shared genetic loci of both …

Overview of atopic dermatitis in different ethnic groups

A Chiricozzi, M Maurelli, L Calabrese, K Peris… - Journal of Clinical …, 2023 - mdpi.com
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a high
prevalence worldwide, including countries from Asia, Africa, and Latin America, and in …

Challenges and future trends in atopic dermatitis

JG Gatmaitan, JH Lee - International Journal of Molecular Sciences, 2023 - mdpi.com
Atopic dermatitis represents a complex and multidimensional interaction that represents
potential fields of preventive and therapeutic management. In addition to the treatment …

Is atopic dermatitis only a skin disease?

A Mesjasz, M Zawadzka, M Chałubiński… - International Journal of …, 2023 - mdpi.com
Atopic dermatitis (AD) is a chronic, pruritic, inflammatory dermatosis that imposes significant
patient and population burdens. In addition to the cutaneous signs and symptoms, growing …

The immunological and structural epidermal barrier dysfunction and skin microbiome in atopic dermatitis-an update

T Çetinarslan, L Kümper… - Frontiers in Molecular …, 2023 - frontiersin.org
Atopic dermatitis (AD) is a common, chronic and relapsing inflammatory skin disease with
various clinical presentations and combinations of symptoms. The pathophysiology of AD is …

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

A Budu-Aggrey, A Kilanowski, MK Sobczyk… - Nature …, 2023 - nature.com
Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide
association studies (GWAS) have identified 71 associated loci. In the current study we …