The meniscus is a fibrocartilaginous structure of the knee joint that serves a crucial role in
joint health and biomechanics. Degeneration or removal of the meniscus is known to lead to …

The knee meniscus is the cushioning fibro-cartilage tissue present in between the femoral
condyles and tibial plateau of the knee joint. It is largely avascular in nature and suffers from …

Cartilage tissue engineering aims to generate functional replacements to treat cartilage
defects from damage and osteoarthritis. Human bone marrow-derived mesenchymal stem …

Background In this comparative study we evaluate the performance of four software tools:
DNAstar-D (DESeq2), DNAstar-E (edgeR), CLC Genomics and Partek Flow for identification …

Background: Osteoarthritis (OA) primarily affects mechanical load-bearing joints. The knee
joint is the most impacted by OA. Knee OA (KOA) occurs in almost all demographic groups …

Osteoarthritis (OA) primarily affects mechanical load-bearing joints, with the knee being the
most common. The prevalence, burden and severity of knee osteoarthritis (KOA) are …

Background Tissue engineering focuses on reconstructing the damaged meniscus by
mimicking the native meniscus. The application of mechanical loading on chondrocyte …

Signals that recapitulate in vitro the conditions found in vivo, such as hypoxia or mechanical
forces, contribute to the generation of tissue-engineered hyaline-like tissues. The cell …

Meniscus fibrochondrocytes (MFCs) experience simultaneous hypoxia and mechanical
loading in the knee joint. Experimental conditions based on these aspects of the native MFC …

Collagenase digestion (d) and cellular outgrowth (og) are the current modalities of meniscus
fibrochondrocytes (MFC) isolation for bioengineering and mechanobiology‐related studies …