Singlet molecular oxygen reactions with nucleic acids, lipids, and proteins

P Di Mascio, GR Martinez, S Miyamoto… - Chemical …, 2019 - ACS Publications
Singlet oxygen (1O2) is a biologically relevant reactive oxygen species capable of efficiently
reacting with cellular constituents. The resulting oxidatively generated damage to nucleic …

Formation of UV-induced DNA damage contributing to skin cancer development

J Cadet, T Douki - Photochemical & Photobiological Sciences, 2018 - pubs.rsc.org
UV-induced DNA damage plays a key role in the initiation phase of skin cancer. When left
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …

Photosensitization reactions of biomolecules: definition, targets and mechanisms

MS Baptista, J Cadet, A Greer… - Photochemistry and …, 2021 - Wiley Online Library
Photosensitization reactions have been demonstrated to be largely responsible for the
deleterious biological effects of UV and visible radiation, as well as for the curative actions of …

Formation and processing of DNA damage substrates for the hNEIL enzymes

AM Fleming, CJ Burrows - Free Radical Biology and Medicine, 2017 - Elsevier
Reactive oxygen species (ROS) are harnessed by the cell for signaling at the same time as
being detrimental to cellular components such as DNA. The genome and transcriptome …

UV and ionizing radiations induced DNA damage, differences and similarities

JL Ravanat, T Douki - Radiation Physics and Chemistry, 2016 - Elsevier
Both UV and ionizing radiations damage DNA. Two main mechanisms, so-called direct and
indirect pathways, are involved in the degradation of DNA induced by ionizing radiations …

Viral disinfection using nonthermal plasma: A critical review and perspectives on the plasma-catalysis system

J Fu, Y Xu, EJ Arts, Z Bai, Z Chen, Y Zheng - Chemosphere, 2022 - Elsevier
The transmission of viral infections via aerosol has become a serious threat to public health.
This has produced an ever-increasing demand for effective forms of viral inactivation …

Spin-Polarized Conceptual Density Functional Theory from the Convex Hull

M Richer, F Heidar-Zadeh… - Journal of Chemical …, 2024 - ACS Publications
We present a new, nonarbitrary, internally consistent, and unambiguous framework for spin-
polarized conceptual density-functional theory (SP-DFT). We explicitly characterize the …

Contribution of oxidation reactions to photo‐induced damage to cellular DNA

J Cadet, D Angelov, P Di Mascio… - Photochemistry and …, 2024 - Wiley Online Library
This review article is aimed at providing updated information on the contribution of
immediate and delayed oxidative reactions to the photo‐induced damage to cellular …

Reactivity of Singlet Oxygen with DNA, an Update

JL Ravanat, E Dumont - Photochemistry and photobiology, 2022 - Wiley Online Library
The reactivity of singlet oxygen with DNA constituents and in particular with the guanine
base has been studied during more than four decades but the exact mechanisms by which …

Recent Advances in Bio‐Compatible Oxygen Singlet Generation and Its Tumor Treatment

ZY **, H Fatima, Y Zhang, Z Shao… - Advanced …, 2022 - Wiley Online Library
Light‐dependent singlet oxygen (1O2) produced in photodynamic therapy (PDT), is a
biologically compatible reactive oxygen species showing the potential to kill tumor cells with …