[HTML][HTML] Precision medicine: disease subty** and tailored treatment
The genomics-based concept of precision medicine began to emerge following the
completion of the Human Genome Project. In contrast to evidence-based medicine …
completion of the Human Genome Project. In contrast to evidence-based medicine …
[HTML][HTML] The need for multi-omics biomarker signatures in precision medicine
Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …
the molecular changes that underlie the development and progression of a wide array of …
Formononetin: a review of its anticancer potentials and mechanisms
Cancer, a complex yet common disease, is caused by uncontrolled cell division and
abnormal cell growth due to a variety of gene mutations. Seeking effective treatments for …
abnormal cell growth due to a variety of gene mutations. Seeking effective treatments for …
Precision medicine: Concept and tools
N Naithani, S Sinha, P Misra, B Vasudevan… - medical journal armed …, 2021 - Elsevier
Precision medicine is the new age medicine and refers to tailoring treatments to a
subpopulation who have a common susceptibility to a particular disease or similar response …
subpopulation who have a common susceptibility to a particular disease or similar response …
Bioinformatics approaches for anti-cancer drug discovery
Drug discovery is important in cancer therapy and precision medicines. Traditional
approaches of drug discovery are mainly based on in vivo animal experiments and in vitro …
approaches of drug discovery are mainly based on in vivo animal experiments and in vitro …
GxVAEs: two joint VAEs generate hit molecules from gene expression profiles
The de novo generation of hit-like molecules that show bioactivity and drug-likeness is an
important task in computer-aided drug discovery. Although artificial intelligence can …
important task in computer-aided drug discovery. Although artificial intelligence can …
Systems biology based drug repositioning for development of cancer therapy
Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …
process by using existing drugs for treatment of a disease rather than its original indication …
[HTML][HTML] Novel strategies for cancer treatment: highlights from the 55th IACR annual conference
S Charmsaz, DM Collins, AS Perry, M Prencipe - 2019 - mdpi.com
While conventional cancer treatments, such as surgery, radiotherapy and chemotherapy,
have been combined for decades in an effort to treat cancer patients, the emergence of …
have been combined for decades in an effort to treat cancer patients, the emergence of …
A multi-omic analysis reveals that Gamabufotalin exerts anti-hepatocellular carcinoma effects by regulating amino acid metabolism through targeting STAMBPL1
P Zheng, D Xu, Y Cai, L Zhu, Q ** of differential protein-protein interactions
Deciphering the variations in the protein interactome is required to reach a systems-level
understanding of tumorigenesis. To accomplish this task, we have considered the clinical …
understanding of tumorigenesis. To accomplish this task, we have considered the clinical …