The role of PD-1 signaling in health and immune-related diseases

RY Chen, Y Zhu, YY Shen, QY Xu, HY Tang… - Frontiers in …, 2023 - frontiersin.org
Programmed cell death 1 receptor (PD-1) and its ligands constitute an inhibitory pathway to
mediate the mechanism of immune tolerance and provide immune homeostasis …

Testicular germ cell tumor: a comprehensive review

A Batool, N Karimi, XN Wu, SR Chen, YX Liu - Cellular and Molecular Life …, 2019 - Springer
Testicular tumors are the most common tumors in adolescent and young men and germ cell
tumors (TGCTs) account for most of all testicular cancers. Increasing incidence of TGCTs …

PD-L1 expression in lung cancer and its correlation with driver mutations: a meta-analysis

M Zhang, G Li, Y Wang, Y Wang, S Zhao, P Haihong… - Scientific reports, 2017 - nature.com
Although many studies have addressed the prognostic value of programmed cell death-
ligand 1 (PD-L1) expression in lung cancer, the results remain controversial. A systematic …

[HTML][HTML] Testicular cancer: Determinants of cisplatin sensitivity and novel therapeutic opportunities

G de Vries, X Rosas-Plaza, MATM van Vugt… - Cancer Treatment …, 2020 - Elsevier
Testicular cancer (TC) is the most common solid tumor among men aged between 15 and
40 years. TCs are highly aneuploid and the 12p isochromosome is the most frequent …

[HTML][HTML] Expression of PD-L1 and prognosis in breast cancer: a meta-analysis

M Zhang, H Sun, S Zhao, Y Wang, H Pu, Q Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
The associations between programmed cell death ligand 1 (PD-L1) and the prognosis of
various cancers have always been a research topic of considerable interest. However, the …

Prognostic value and immunological role of PDCD1 gene in pan-cancer

Y Miao, J Wang, Q Li, W Quan, Y Wang, C Li… - International …, 2020 - Elsevier
Objective Identify the prognostic value and investigate the association between programmed
cell death 1 (PDCD1) gene expression and immune infiltration in pan-cancer. Methods We …

[HTML][HTML] Phase II trial of pembrolizumab in patients with platinum refractory germ-cell tumors: a Hoosier Cancer Research Network Study GU14-206

N Adra, LH Einhorn, SK Althouse, NR Ammakkanavar… - Annals of …, 2018 - Elsevier
Background Despite remarkable results with salvage standard-dose or high-dose
chemotherapy~ 15% of patients with relapsed germ-cell tumors (GCT) are incurable …

The clinicopathological and prognostic significance of PD-L1 expression in gastric cancer: a meta-analysis of 10 studies with 1,901 patients

M Zhang, Y Dong, H Liu, Y Wang, S Zhao, Q Xuan… - Scientific reports, 2016 - nature.com
The prognostic value of programmed death-ligand 1 (PD-L1) in gastric cancer (GC) remains
controversial. To clarify this problem, we performed a meta-analysis of research studies …

[HTML][HTML] PD-1/PD-L1 pathway: A double-edged sword in periodontitis

X Liu, L Yang, X Tan - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Periodontitis is a disease caused by infection and immunological imbalance, which often
leads to the destruction of periodontal tissue. Programmed death protein 1 (PD-1) and its …

Advances in diagnosis and treatment of testicular cancer

M Chovanec, L Cheng - bmj, 2022 - bmj.com
Testicular cancer is a curable cancer. The success of physicians in curing the disease is
underpinned by multidisciplinary advances. Cisplatin-based combination chemotherapy and …