Recent progress in the science of complex coacervation

CE Sing, SL Perry - Soft Matter, 2020 - pubs.rsc.org
Complex coacervation is an associative, liquid–liquid phase separation that can occur in
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …

[HTML][HTML] Coacervates as models of membraneless organelles

NA Yewdall, AAM André, T Lu, E Spruijt - Current Opinion in Colloid & …, 2021 - Elsevier
Coacervates are condensed liquid-like droplets, usually formed with oppositely charged
polymeric molecules. They have been studied extensively in colloid and interface science …

A graph representation of molecular ensembles for polymer property prediction

M Aldeghi, CW Coley - Chemical Science, 2022 - pubs.rsc.org
Synthetic polymers are versatile and widely used materials. Similar to small organic
molecules, a large chemical space of such materials is hypothetically accessible …

Polyelectrolyte complex coacervates: Recent developments and new frontiers

AM Rumyantsev, NE Jackson… - Annual Review of …, 2021 - annualreviews.org
Polyelectrolyte complex coacervates represent a wide class of materials with applications
ranging from coatings and adhesives to pharmaceutical technologies. They also underpin …

Polyelectrolyte complex coacervation across a broad range of charge densities

AE Neitzel, YN Fang, B Yu, AM Rumyantsev… - …, 2021 - ACS Publications
Polyelectrolyte complex coacervates of homologous (co) polyelectrolytes with a near-ideally
random distribution of a charged and neutral ethylene oxide comonomer were synthesized …

Hydrophobic ion pairing: encapsulating small molecules, peptides, and proteins into nanocarriers

KD Ristroph, RK Prud'homme - Nanoscale advances, 2019 - pubs.rsc.org
Hydrophobic ion pairing has emerged as a method to modulate the solubility of charged
hydrophilic molecules ranging in class from small molecules to large enzymes. Charged …

RNA-based coacervates as a model for membraneless organelles: formation, properties, and interfacial liposome assembly

WM Aumiller Jr, F Pir Cakmak, BW Davis, CD Keating - Langmuir, 2016 - ACS Publications
Liquid–liquid phase separation is responsible for formation of P granules, nucleoli, and
other membraneless subcellular organelles composed of RNA and proteins. Efforts to …

Coacervate droplets for synthetic cells

Z Lin, T Beneyton, JC Baret, N Martin - Small Methods, 2023 - Wiley Online Library
The design and construction of synthetic cells–human‐made microcompartments that mimic
features of living cells–have experienced a real boom in the past decade. While many efforts …

Complex coacervate‐based materials for biomedicine

WC Blocher, SL Perry - Wiley Interdisciplinary Reviews …, 2017 - Wiley Online Library
There has been increasing interest in complex coacervates for deriving and transporting
biomaterials. Complex coacervates are a dense, polyelectrolyte‐rich liquid that results from …

Protein encapsulation using complex coacervates: what nature has to teach us

WC Blocher McTigue, SL Perry - Small, 2020 - Wiley Online Library
Protein encapsulation is a growing area of interest, particularly in the fields of food science
and medicine. The sequestration of protein cargoes is achieved using a variety of methods …