The contribution of evolutionary game theory to understanding and treating cancer
B Wölfl, H Te Rietmole, M Salvioli… - Dynamic Games and …, 2022 - Springer
Evolutionary game theory mathematically conceptualizes and analyzes biological
interactions where one's fitness not only depends on one's own traits, but also on the traits of …
interactions where one's fitness not only depends on one's own traits, but also on the traits of …
In silico modelling of cancer nanomedicine, across scales and transport barriers
Nanoparticles promise to improve the treatment of cancer through their increasingly
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …
Integrating mechanism-based modeling with biomedical imaging to build practical digital twins for clinical oncology
Digital twins employ mathematical and computational models to virtually represent a
physical object (eg, planes and human organs), predict the behavior of the object, and …
physical object (eg, planes and human organs), predict the behavior of the object, and …
Patient-specific, mechanistic models of tumor growth incorporating artificial intelligence and big data
Despite the remarkable advances in cancer diagnosis, treatment, and management over the
past decade, malignant tumors remain a major public health problem. Further progress in …
past decade, malignant tumors remain a major public health problem. Further progress in …
Theranostic digital twins: Concept, framework and roadmap towards personalized radiopharmaceutical therapies
Radiopharmaceutical therapy (RPT) is a rapidly develo** field of nuclear medicine, with
several RPTs already well established in the treatment of several different types of cancers …
several RPTs already well established in the treatment of several different types of cancers …
Image-based personalization of computational models for predicting response of high-grade glioma to chemoradiation
DA Hormuth, KA Al Feghali, AM Elliott, TE Yankeelov… - Scientific reports, 2021 - nature.com
High-grade gliomas are an aggressive and invasive malignancy which are susceptible to
treatment resistance due to heterogeneity in intratumoral properties such as cell proliferation …
treatment resistance due to heterogeneity in intratumoral properties such as cell proliferation …
[HTML][HTML] Cancer modeling: From mechanistic to data-driven approaches, and from fundamental insights to clinical applications
Cancer is still one of the major causes of death worldwide. Even if its comprehension is
improving continuously, the complexity and heterogeneity of this group of diseases …
improving continuously, the complexity and heterogeneity of this group of diseases …
Opportunities for improving brain cancer treatment outcomes through imaging-based mathematical modeling of the delivery of radiotherapy and immunotherapy
Immunotherapy has become a fourth pillar in the treatment of brain tumors and, when
combined with radiation therapy, may improve patient outcomes and reduce the …
combined with radiation therapy, may improve patient outcomes and reduce the …
[HTML][HTML] Mathematical modeling of radiotherapy and its impact on tumor interactions with the immune system
Radiotherapy is a primary therapeutic modality widely utilized with curative intent.
Traditionally tumor response was hypothesized to be due to high levels of cell death …
Traditionally tumor response was hypothesized to be due to high levels of cell death …
Zebrafish avatars towards personalized medicine—a comparative review between avatar models
B Costa, MF Estrada, RV Mendes, R Fior - Cells, 2020 - mdpi.com
Cancer frequency and prevalence have been increasing in the past decades, with
devastating impacts on patients and their families. Despite the great advances in targeted …
devastating impacts on patients and their families. Despite the great advances in targeted …